In patients presenting with chest pain complaints and an intermediate risk of coronary artery disease, Multi-Slice Computed Tomography (MSCT) will have a higher specificity as compared to myocardial perfusion imaging (MPI). Accordingly, MSCT may…
ID
Bron
Verkorte titel
Aandoening
Patients with suspected coronary artery disease
Ondersteuning
Onderzoeksproduct en/of interventie
Uitkomstmaten
Primaire uitkomstmaten
MSCT may improve (as compared to MPI) the diagnosis of patients presenting with chest pain complaints and an intermediate likelihood of CAD.<br>
Particularly in these patients, a non-invasive test with a high specificity (to exclude CAD) is needed to allow optimal management of patients. Currently, MPI is used for this purpose, but the specificity of MPI is suboptimal (70%).
Achtergrond van het onderzoek
N/A
Doel van het onderzoek
In patients presenting with chest pain complaints and an intermediate risk of coronary artery disease, Multi-Slice Computed Tomography (MSCT) will have a higher specificity as compared to myocardial perfusion imaging (MPI). Accordingly, MSCT may serve as an accurate first-line evaluation tool.
Onderzoeksopzet
N/A
Onderzoeksproduct en/of interventie
MSCT coronary angiography in addition to myocardial perfusion imaging (MPI).
Publiek
Department of Cardiology,
P.O. Box 9600
J.J. Bax
Albinusdreef 2
Leiden 2300 RC
The Netherlands
+31 (0)71 5262020
j.j.bax@lumc.nl
Wetenschappelijk
Department of Cardiology,
P.O. Box 9600
J.J. Bax
Albinusdreef 2
Leiden 2300 RC
The Netherlands
+31 (0)71 5262020
j.j.bax@lumc.nl
Belangrijkste voorwaarden om deel te mogen nemen (Inclusiecriteria)
Adult patients (having obtained legal majority age) with chest pain complaints and an intermediate pre-test likelihood of CAD (based on the Diamond and Forrester method) with the need for additional imaging studies to evaluate the presence/absence of CAD.
Belangrijkste redenen om niet deel te kunnen nemen (Exclusiecriteria)
Fertile women, patients with severe renal failure, patients presenting with a known allergy to iodine contrast media, patients included in another clinical trial, patients under guardianship, and patients whose degree of cooperation is incompatible with carrying out the study.
Opzet
Deelname
Opgevolgd door onderstaande (mogelijk meer actuele) registratie
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Andere (mogelijk minder actuele) registraties in dit register
Geen registraties gevonden.
In overige registers
| Register | ID |
|---|---|
| NTR-new | NL446 |
| NTR-old | NTR486 |
| Ander register | : N/A |
| ISRCTN | ISRCTN65675235 |