Primary care decision rule for chest pain using the Marburg Heart Score and troponin point of care test

A clustered randomized controlled trial to determine the effectiveness and safety of a decision rule compared to the usual care for patients presenting with non-traumatic chest pain in primary care in the Netherlands. The decision rule is a combination of the Marburg Heart Score and a hs-troponin I point of care test. Primary end points are the safety of the decision rule (accuracy) and the effectiveness (referrals to secondary care).

We hypothesize that by use of the decision rule, compared to usual care, the GP’s specificity will increase, following a 10% decrease in false-positive referrals. Provided that sensitivity sufficient to guarantee patient safety

Inclusion, and 1, 6 and 26 weeks after inclusion

Clinical decision rule