N/A
ID
Bron
Aandoening
ADHD, atomoxetine, electroencephalography (EEG), event-related potential (ERP), attention, inhibition
Ondersteuning
Faculty of Science
Department of Psychopharmacology
Faculty of Science
Department of Psychopharmacology
Onderzoeksproduct en/of interventie
Uitkomstmaten
Primaire uitkomstmaten
Primary outcome measures are:<br>
The weaving of the car during the driving test, i.e. the Standard Deviation of Lateral Position (SDLP), the P3a measured in an auditory oddball task which is suggested to reflect attention orienting/distraction, and the stop signal reaction time and P3 measured in a stop task which is suggested to be associated with response inhibition.
Achtergrond van het onderzoek
N/A
Doel van het onderzoek
N/A
Onderzoeksopzet
Each measure is acquired twice, timepoint: 0 and 5-7 days.
Onderzoeksproduct en/of interventie
1. Atomoxetine;
2. Placebo.
Publiek
A.E. Wester
Sorbonnelaan 16
Utrecht 3584 CA
The Netherlands
+31(0)302537768
A.E.Wester@uu.nl
Wetenschappelijk
A.E. Wester
Sorbonnelaan 16
Utrecht 3584 CA
The Netherlands
+31(0)302537768
A.E.Wester@uu.nl
Belangrijkste voorwaarden om deel te mogen nemen (Inclusiecriteria)
1. Adult men and women diagnosed with ADHD (DSM IV, APA 1994), aged 21-55 years;
2. Written informed consent;
3. Possession of a valid driver’s license for at least 3 years;
4. For women of childbearing potential, a negative urine beta-HCG pregnancy test result at test days;
5. Normal static binocular acuity, corrected or uncorrected;
6. Normal hearing;
7. Be considered as reliable and mentally capable of adhering to the protocol.
Belangrijkste redenen om niet deel te kunnen nemen (Exclusiecriteria)
1. Depression or anxiety disorder, unless controlled and stable with medication (SSRI);
2. IQ<75;
3. Current drug use (positive urine drug screen on the presence of amphetamines (including MDMA), barbiturates, benzodiazepines, cocaine, and opiates at test days);
4. Use of psychoactive medication, except SSRI;
5. Positive alcohol breath test;
6. Prior enrolment in the same study;
7. Participation in another clinical trial.
Opzet
Deelname
Opgevolgd door onderstaande (mogelijk meer actuele) registratie
Geen registraties gevonden.
Andere (mogelijk minder actuele) registraties in dit register
Geen registraties gevonden.
In overige registers
| Register | ID |
|---|---|
| NTR-new | NL1992 |
| NTR-old | NTR2109 |
| Ander register | METC Universiteit Utrecht : 08/225 |
| ISRCTN | ISRCTN wordt niet meer aangevraagd. |