The CPC-mouthrinse inhibit 15% less of 'de novo' plaqueformation compared to a placebo and hexitine over a period of 3 days in a non-brushing model.
ID
Bron
Verkorte titel
Aandoening
Gingivitis
Ondersteuning
Onderzoeksproduct en/of interventie
Uitkomstmaten
Primaire uitkomstmaten
Bleeding on Marginal Probing (BOMP) – Angular Bleeding Index (Van der Weijden 1994).<br>
This score will be done at session 1, 2 and 3. <br><br>
The gingiva is lightly dried with compressed air and lightly probed with a probe. The probe is inserted into the gingival crevice to a depth of approximately 2mm or until slight resistance is felt. The probe is run gently along the marginal gingival holding the probe at a an angle of approximately 60 degrees to the longitudinal axis of the tooth and in contact with the sulcular epithelium. Minimum axial force is used to avoid undue penetration in the tissue. The probe is moved around the crevice gently stretching the epithelium. A bleeding score is given to six gingival areas of the tooth. <br>These are the disto-vestibular, vestibular, mesio-vestibular, disto-lingual, lingual and the mesio-lingual regions.
Achtergrond van het onderzoek
The present study aims at testing whether a CPC-mouthrinse has a potential to inhibit ‘de novo’ plaque formation as compared to a placebo and hexetidine.
Doel van het onderzoek
The CPC-mouthrinse inhibit 15% less of 'de novo' plaqueformation compared to a placebo and hexitine over a period of 3 days in a non-brushing model.
Onderzoeksopzet
Session 1:
-Professional oral profylaxis
-Measurements (after 3 days of profylaxis)
Session 2:
-Professional oral profylaxis
-Measurements (after 3 days of profylaxis)
Session 3:
-Professional oral profylaxis
-Measurements (after 3 days of profylaxis)
Onderzoeksproduct en/of interventie
At session 1:
Subjects have to rinse 3 times a day during 3 days with CPC-mouthrinse, Hexitine mouthrinse or a placebo mouthrinse.
The above mentioned procedure will be repeated also at session 2 and 3 in order to have all subjects run the protocol with all three products.
Publiek
Department of Parodentology
P.A. Versteeg
Louwesweg 1
Amsterdam 1066 EA
The Netherlands
020-5188548
p.versteeg@acta.nl
Wetenschappelijk
Department of Parodentology
P.A. Versteeg
Louwesweg 1
Amsterdam 1066 EA
The Netherlands
020-5188548
p.versteeg@acta.nl
Belangrijkste voorwaarden om deel te mogen nemen (Inclusiecriteria)
1. Be between the ages of 18 and 70
2. Be in good general health as determined by the investigator/designee based on a review of the medical history/update
3. Possess at least 5 evaluable teeth in each quadrant in the lower jaw
Belangrijkste redenen om niet deel te kunnen nemen (Exclusiecriteria)
1. Orthodontic banding or wires or partial dentures
2. Severe periodontal disease (no sites with PPD > 5mm), including but not limited to purulent exudate, generalized mobility, and or severe recession
3. Any disease or conditions that could be expected to interfere with examination procedures or the subject safely completing the trial.
Opzet
Deelname
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In overige registers
| Register | ID |
|---|---|
| NTR-new | NL1283 |
| NTR-old | NTR1329 |
| Ander register | : MEC 08/112 |
| ISRCTN | ISRCTN wordt niet meer aangevraagd |