Control of COVID-19 in hospitals

Since December 2019, the world has been in the grip of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and the disease it causes, coronavirus disease 2019 (COVID-19). Effective management of this pandemic requires estimation of the burden of disease. Currently available literature on COVID-19 mostly represents severe cases admitted to the hospital; data on mild and unsuspected clinical presentations and asymptomatic infections are largely unknown. Sero-epidemiologic studies are urgently needed to help uncover the burden of disease, in particular the rate of asymptomatic infections, and to get better estimates on the incidence of disease. Sero-epidemiologic studies can help identify the extent to which the virus has spread and whether this has led to protective immunity. Such information could help guide infection control policies. This study will evaluate the sero-epidemiology of SARS-CoV-2 in healthcare workers (HCWs) in Dutch hospitals in regions with varying incidence of COVID-19.

Not applicable, descriptive study

Enrolment (baseline), 3-months after enrolment. In case of symptoms: day of onset, 2 (+2) days symptom free, 8 (+2) days symptom free

Not applicable