To evaluate if the pregnancy rate, number of ongoing pregnancies and the number of live births after IUI increases as the time between the production of semen and the IUI is shortened.
ID
Bron
Verkorte titel
Aandoening
Subfertility
Ondersteuning
Onderzoeksproduct en/of interventie
Uitkomstmaten
Primaire uitkomstmaten
Ongoing pregnancy rate per patient couple (positive fetal cardiac activity 10 weeks after IUI).
Achtergrond van het onderzoek
A single centre randomized controlled trial to evaluate if the pregnancy rate, number of ongoing pregnancies and the number of live births after IUI increases as the time between the production of semen and the IUI is shortened in couples with unexplained, cervical factor or male subfertility at the VU University Medical Center, The Netherlands.
Doel van het onderzoek
To evaluate if the pregnancy rate, number of ongoing pregnancies and the number of live births after IUI increases as the time between the production of semen and the IUI is shortened.
Onderzoeksopzet
N/A
Onderzoeksproduct en/of interventie
Patients are inseminated approximately 3-4 hours after the production of semen (Group I, current practice VUmc) or patients are inseminated as soon as possible after the production of semen (Group II, intervention group).
Publiek
PO box 7057
C.G. Vergouw
Amsterdam 1007 MB
The Netherlands
+31 (0)20 4443229
carlijn.vergouw@vumc.nl
Wetenschappelijk
PO box 7057
C.G. Vergouw
Amsterdam 1007 MB
The Netherlands
+31 (0)20 4443229
carlijn.vergouw@vumc.nl
Belangrijkste voorwaarden om deel te mogen nemen (Inclusiecriteria)
Patients who start their first IUI treatment. All subsequent cycles fall within this study. Only patients who undergo six IUI cycles, three times in a natural cycle and three times in a stimulated cycle, fall within this study. Patients who start a new IUI treatment after an ongoing pregnancy. Both IUI performed in a natural cycle and stimulated cycles fall within this study. Patients with well-adjusted, non-endocrine hormonal pathology fall within this study.
Belangrijkste redenen om niet deel te kunnen nemen (Exclusiecriteria)
Patients who have IUI with donorsemen. Patients in which the semen was obtained in a different way than masturbation (bladder irrigation, electrical stimulation). Patients who have less than 0.5 million progressive motile sperm left over after work-up of semen. Patients with polycystic ovarian syndrome (PCOS). Patients with imminent ovarian failure (basal FSH> 10 IU / l).
Opzet
Deelname
Opgevolgd door onderstaande (mogelijk meer actuele) registratie
Geen registraties gevonden.
Andere (mogelijk minder actuele) registraties in dit register
Geen registraties gevonden.
In overige registers
| Register | ID |
|---|---|
| NTR-new | NL2996 |
| NTR-old | NTR3144 |
| Ander register | METc VUmc : 2011/219 |
| ISRCTN | ISRCTN wordt niet meer aangevraagd. |