In migraine, a biomarker (either via neuroimaging or biochemical profiling) can be found to distinguish patient from non-patients and to understand how migraine attacks initiate and develop
ID
Bron
Verkorte titel
Aandoening
Migraine
Ondersteuning
Onderzoeksproduct en/of interventie
Uitkomstmaten
Primaire uitkomstmaten
Depends on sub-study protocol
Achtergrond van het onderzoek
Biochemic profiling in migraine: a lare study into clinical, neuroimaging and biochemical (a.o. serum and cerebrospinal fluid) profiling of migraine patients during different phases of the migraine attack, in comparison with non-headache individuals. The overall study includes up to 500 participants, distributed over varioud substudies. Both spontaneous and nitroglycerin-triggered migraine attacks are studied. The study is mainly observational; the intervention in some sub-studies is nitroglycerin-triggering, which is an international well-esthablished model to facilitate the studying of migraine attacks
Doel van het onderzoek
In migraine, a biomarker (either via neuroimaging or biochemical profiling) can be found to distinguish patient from non-patients and to understand how migraine attacks initiate and develop
Onderzoeksopzet
Start 2008; in accordance to local METC multiple extensions
Onderzoeksproduct en/of interventie
In most sub-study protocols: none; in some: nitroglycerin triggering
Publiek
Wetenschappelijk
Belangrijkste voorwaarden om deel te mogen nemen (Inclusiecriteria)
Migraine headaches; over 18 years of age
Belangrijkste redenen om niet deel te kunnen nemen (Exclusiecriteria)
Other primary headaches; other neurologis conditions or medication that interfere with specific sub-study goals
Opzet
Deelname
Voornemen beschikbaar stellen Individuele Patiënten Data (IPD)
Toelichting
Opgevolgd door onderstaande (mogelijk meer actuele) registratie
Geen registraties gevonden.
Andere (mogelijk minder actuele) registraties in dit register
Geen registraties gevonden.
In overige registers
| Register | ID |
|---|---|
| NTR-new | NL8203 |
| Ander register | METC LUMC : METC P07.079 |