A goal directed nutritional support can reduce sarcopenia in surgical esophagus patients.
ID
Bron
Verkorte titel
Aandoening
Esophageal cancer patients undergoing an esophagectomy
Ondersteuning
Secundary
Gelre Hospital Apeldoorn
Onderzoeksproduct en/of interventie
Uitkomstmaten
Primaire uitkomstmaten
Sarcopenia (muscle loss) measured by psoas muscle index by a CT-scan
Achtergrond van het onderzoek
In one Dutch hospital cancer patients undergoing esophagectomy will receive a goal directed nutritional support; in another Dutch hospital care as usual will be provided.
Doel van het onderzoek
A goal directed nutritional support can reduce sarcopenia in surgical esophagus patients.
Onderzoeksopzet
At baseline, one-year after surgery for the primary outcomes. Other measurements will also be performed before surgery, and 3 and 6 months after surgery.
Onderzoeksproduct en/of interventie
Strict nutrtional protocol consisting of:
• One dietitian: case manager during all stages of treatment
• Use PG-SGA-questionnaire before consult
• Weekly registration of nutritional intake
• Energy needs measured by indirect colorimetry
• Proactive nutritional support
Publiek
Marjo Campmans-Kuijpers
Postbus 30.001
Groningen 9700RB
The Netherlands
06-55256587
M.J.E.Campmans-Kuijpers@UMCG.nl
Wetenschappelijk
Marjo Campmans-Kuijpers
Postbus 30.001
Groningen 9700RB
The Netherlands
06-55256587
M.J.E.Campmans-Kuijpers@UMCG.nl
Belangrijkste voorwaarden om deel te mogen nemen (Inclusiecriteria)
• Patients that undergo a (minimally invasive or hybrid: laparoscopy and thoracotomy or conventional open surgery) esophagectomy for cancer with cervical or intrathoracic anastomosis
• Written informed consent
• Age > 18 years
• Histologically confirmed, previously untreated esophageal cancer
• Considered suitable for radical surgery with curative intent.
• Squamous cell carcinoma, adenocarcinoma, and undifferentiated carcinoma are included.
• Tumor location included the upper, middle, lower thirds of the esophagus and esophagogastric junction tumors, but excluded postcricoid cancers.
Belangrijkste redenen om niet deel te kunnen nemen (Exclusiecriteria)
• Salvage esophagectomy; after previous histologically confirmed esophageal cancer treated by ‘definitive’ radio- or radiochemotherapy
• Inability to provide written consent or inability to fill out questionnaires
• Previous or concomitant malignant disease, apart from basal-cell carcinoma
• Cervical lymph-node involvement or evidence of metastases.
• Karnofsky Performance Status < 80
Opzet
Deelname
Opgevolgd door onderstaande (mogelijk meer actuele) registratie
Geen registraties gevonden.
Andere (mogelijk minder actuele) registraties in dit register
Geen registraties gevonden.
In overige registers
| Register | ID |
|---|---|
| NTR-new | NL6179 |
| NTR-old | NTR6326 |
| CCMO | NL57787.042.16 |