Use of this walk-bike in daily life extends the range and everyday mobility of IPF patients, thereby decreases the level of dependency and social isolation, factors that are associated with quality of life. If, with this low-cost intervention, daily…
ID
Bron
Verkorte titel
Aandoening
Idiopathic pulmonary fibrosis (IPF), walk-bike, quality of life, exercise capacity
Ondersteuning
Onderzoeksproduct en/of interventie
Uitkomstmaten
Primaire uitkomstmaten
Change in total score in health-related quality of life questionnaire SGRQ
Achtergrond van het onderzoek
IPF is a devastating progressive disease with limited treatment options. Dyspnea and fatigue lead to a reduction of daily physical activities, exercise tolerance, muscle strength and quality of life. Problems reported by IPF patients are social isolation, increased level of dependency and immobility.We hypothesized that use of this walk-bike in daily life extends the range and everyday mobility of IPF patients, thereby decreases the level of dependency and social isolation, factors that are associated with quality of life. If, with this low-cost intervention, daily activities of IPF patients increase, exercise capacity might improve too. The objective of this pilot study is to assess the efficacy of the ¡°walk-bike¡± on quality of life and exercise capacity in IPF patients. In this crossover pilot study participants will be randomly allocated to either an 8 weeks-exercise intervention (using a walk-bike) or receive standard treatment only. After the follow-up visit at week 9 patient will cross-over to the other group.
Doel van het onderzoek
Use of this walk-bike in daily life extends the range and everyday mobility of IPF patients, thereby decreases the level of dependency and social isolation, factors that are associated with quality of life. If, with this low-cost intervention, daily activities of IPF patients increase, exercise capacity might improve too.
Onderzoeksopzet
There are three study visits:
-Baseline measurements before randomly allocation to either intervention group (use of walk-bike) or control group.
-Post measurements at week 9
-Crossover to other group.
-Post measurements at week 18.
Onderzoeksproduct en/of interventie
Use of a walk-bike in daily life during 8 weeks, with a minimum of 1 hour per day. The patient will be asked to record the time using the walk-bike in a diary. At baseline instructions will be given and a training under supervision.
The control group will receive standard treatment only.
Publiek
Wetenschappelijk
Belangrijkste voorwaarden om deel te mogen nemen (Inclusiecriteria)
-IPF patients
-Diagnosis of IPF, including probable and possible diagnosis according to ATS/ERS criteria
-Written informed consent
-TLCOc ¡Ý 30%(pred) and FVC ¡Ý 50% (pred)
-6MWD ¡Ý 150 m
-Being clinically stable
-Absolute decline in TLCOc and FVC should be less than 10% in the past 6 months.
Belangrijkste redenen om niet deel te kunnen nemen (Exclusiecriteria)
-Participation in a formal rehabilitation program within 4 months of start of study
-Musculoskeletal disorders
-Severe cardiac diseases (ejection fraction < 30%, daily angina, or otherwise specified by treating cardiologist)
-Unable to understand informed consent
-Other conditions that hamper the use of a walk-bike
Opzet
Deelname
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Andere (mogelijk minder actuele) registraties in dit register
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In overige registers
Register | ID |
---|---|
NTR-new | NL5186 |
NTR-old | NTR5334 |
Ander register | NL45411.078.14 : MEC- 2014-047 Erasmus MC |