Dynamic hyperinflation in patients with COPD is not different in cardio pulmonary exercise testing (CPET) from dynamic hyperinflation in metronome paced hyperventilation test (MPH).
ID
Bron
Aandoening
COPD, dynamic hyperinflation.
dynamische hyperinflatie.
Ondersteuning
pulmonary function department
Medical Centre Leeuwarden
Onderzoeksproduct en/of interventie
Uitkomstmaten
Primaire uitkomstmaten
Difference in IC manoeuvre (in ml) between basal and post-test value of both tests (CPET and MPH).
Achtergrond van het onderzoek
Referring to paper of AJMC Laheije et al (Clin Physiol Funct Imaging 2013;33:62-69) in this observational study, we want to investigate whether in our hands (Medical Centre Leeuwarden, pulmonary function department) there is no difference between dynamic hyperinflation (assessed by change in inspiratory capacity) in patients with COPD between metronome paced hyperventilation test (MPH) and cardio pulmonary exercise testing (CPET) as gold standard test.
Doel van het onderzoek
Dynamic hyperinflation in patients with COPD is not different in cardio pulmonary exercise testing (CPET) from dynamic hyperinflation in metronome paced hyperventilation test (MPH).
Onderzoeksopzet
See above: interventions
Onderzoeksproduct en/of interventie
Addition of Metronome paced hyperventilation test prior to CPET: in both tests IC manoeuvres shall be performed as a measure for dynamic hyperinflation.
All participants will perform both tests.
CPET (bycicle): IC manouevres: basal and at maximum exercise.
MPH: IC manoeuvres: basal and after 20 sec ventilating at double resting respiratory rate.
Publiek
MCL
Leeuwarden
J. Maten, van der
Leeuwarden
The Netherlands
+31 (0)58 286 6190
j.maten@znb.nl
Wetenschappelijk
MCL
Leeuwarden
J. Maten, van der
Leeuwarden
The Netherlands
+31 (0)58 286 6190
j.maten@znb.nl
Belangrijkste voorwaarden om deel te mogen nemen (Inclusiecriteria)
1. COPD with FEV1/VC< LLN. (All GOLD classes included)
2. Age > 17 years.
3. Sent for CPET (all indications) by pulmonologist.
Belangrijkste redenen om niet deel te kunnen nemen (Exclusiecriteria)
1. Not able to perform Inspiratory Capacity manoeuvre well
2. No informed consent
Opzet
Deelname
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Andere (mogelijk minder actuele) registraties in dit register
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In overige registers
| Register | ID |
|---|---|
| NTR-new | NL4613 |
| NTR-old | NTR4764 |
| Ander register | Regionale Toetsingscommissie Patiëntgebonden Onderzoek Leeuwarden : RTPO 924 |