Triclosan coated sutures might have an positive effect on wound healing and thus can improve scar quality.
ID
Bron
Verkorte titel
Aandoening
Vicryl Plus
coated sutures
Triclosan
wound healing/ wondgenezing
Ondersteuning
Onderzoeksproduct en/of interventie
Uitkomstmaten
Primaire uitkomstmaten
Wound healing: wound dehiscence and complications are registrated.
Achtergrond van het onderzoek
Wound infection is a major contributor to postoperative morbidity. One
potential cause or co-factor is the use of suture material. A recently
introduced subcutaneous suture is coated with triclosan (TC), an antiseptic
drug. It is suggested to reduce wound complications and improve scar
quality.
Methods:
To investigate the effect of TC on wound healing a double blind prospective
study in women undergoing a breast reduction was performed. Each patient was
her own control. After randomization the TC coated sutures were used either
on the left or right side. The contra lateral side was used as the control.
The incidence of dehiscence, postoperative redness and subjective parameters
of scar quality were studied.
Doel van het onderzoek
Triclosan coated sutures might have an positive effect on wound healing and thus can improve scar quality.
Onderzoeksopzet
N/A
Onderzoeksproduct en/of interventie
Standard suture on control site;
triclosan coated suture on study site.
Publiek
Wetenschappelijk
Belangrijkste voorwaarden om deel te mogen nemen (Inclusiecriteria)
1. Women between 16 and 65 years of age with bilateral breast size higher than cup DD;
2. Clinical complaints such as intertrigo, head neck and/or shoulder complaints;
3. Undergoing a breast reduction.
Belangrijkste redenen om niet deel te kunnen nemen (Exclusiecriteria)
1. Patients with:
a. diabetes;
b. skin diseases;
c. history of keloid formation;
d. use of corticosteroids and other immunosuppressive medication;
e. metabolic and/or degenerative diseases.
Opzet
Deelname
Opgevolgd door onderstaande (mogelijk meer actuele) registratie
Geen registraties gevonden.
Andere (mogelijk minder actuele) registraties in dit register
Geen registraties gevonden.
In overige registers
| Register | ID |
|---|---|
| NTR-new | NL957 |
| NTR-old | NTR983 |
| Ander register | : N/A |
| ISRCTN | ISRCTN32724539 |