Absence of EEG reactivity predicts outcome after cardiac arrest
ID
Bron
Verkorte titel
Aandoening
"cardiac arrest"; "resuscitation"; "post-anoxia"; "post-anoxic coma"; "hartstilstand"; "reanimatie"; "EEG"; "EEG reactivity"; "EEG reactiviteit"; "continuous EEG"; "continue EEG registratie"
Ondersteuning
Onderzoeksproduct en/of interventie
Uitkomstmaten
Primaire uitkomstmaten
Best neurological outcome (Cerebral performance category scale) at 3 months
Achtergrond van het onderzoek
Part of regular EEG examination is testing whether the EEG changes upon external stimulation, EEG reactivity. However, testing protocol and definition of EEG reactivity is often not clearly defined. Despite this, in cardiac arrest patients, reactivity is thought to be a reliable prognosticator. We aim to determine the prognostic value and added value besides other markers for prognosis of EEG reactivity testing in cardiac arrest patients.
Doel van het onderzoek
Absence of EEG reactivity predicts outcome after cardiac arrest
Onderzoeksopzet
ICU discharge; 3 months post-resuscitation; 6 months post-resuscitation
Onderzoeksproduct en/of interventie
None
Publiek
Wetenschappelijk
Belangrijkste voorwaarden om deel te mogen nemen (Inclusiecriteria)
- patients after cardiac arrest
- age of 18 or older
- continuous EEG monitoring with at least 8 electrodes started within 24h post-resuscitation
- Targeted temperatur management treatment as per hospital protocol
Belangrijkste redenen om niet deel te kunnen nemen (Exclusiecriteria)
- Known history of another medical condition with life expectancy <6 months
- Any progressive brain illness, such as a brain tumor or neurodegenerative disease Pre-admission
- Modified Rankin Scale of 4 or lower
- Reason other than neurological condition to withdraw treatment
- Follow-up impossible due to logistic reasons
- Severe head injury
Opzet
Deelname
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In overige registers
| Register | ID |
|---|---|
| NTR-new | NL6084 |
| NTR-old | NTR6231 |
| Ander register | : W15_287 # 15.0356 |