The JES-classification can be used for predicting invasion depth in esophageal squamous cell carcinoma (ESCC) in Western patients
ID
Bron
Verkorte titel
Aandoening
All patients with a suspicious or known (pre)malignant esophageal squamous cell lesion
Ondersteuning
Onderzoeksproduct en/of interventie
Uitkomstmaten
Primaire uitkomstmaten
The overall accuracy of the JES-classification for predicting the invasion depth of ESCC
Achtergrond van het onderzoek
The objective of this study is to validate the JES-classification for prediction of invasion depth of superficial squamous cell carcinoma by Western endoscopists in a Western population. This is a multicenter observational study.
Doel van het onderzoek
The JES-classification can be used for predicting invasion depth in esophageal squamous cell carcinoma (ESCC) in Western patients
Onderzoeksopzet
After collection of all available endoscopic photos and videos from previously treated patients, the photos and videos will be analyzed by multiple expert endoscopists and non-expert endoscopists.
Onderzoeksproduct en/of interventie
Endoscopic photos and videos of white light endoscopy (WLE), magnification endoscopy, NBI and lugol’s iodine staining from previously treated patients with ESCC will be collected. The photos and videos will be analyzed prospectively by multiple assessors. The ESCC lesions will be scored on their invasion depth by using the microvessel pattern according to the JES-classification.
Publiek
Wetenschappelijk
Belangrijkste voorwaarden om deel te mogen nemen (Inclusiecriteria)
In order to be eligible to participate in this study, a subject must meet all of the following criteria:
- Western patients with a suspicious or known (pre)malignant esophageal squamous cell lesion
- Photos and videos available using WLE, magnification endoscopy, NBI, and (when available) lugol’s iodine staining.
Belangrijkste redenen om niet deel te kunnen nemen (Exclusiecriteria)
A potential subject who meets any of the following criteria will be excluded from any analysis with regard to the prediction of invasion depth:
- No data on histological invasion depth available.
- Patients who underwent esophagectomy with neoadjuvant (chemo)radiation therapy.
Opzet
Deelname
Voornemen beschikbaar stellen Individuele Patiënten Data (IPD)
Toelichting
Opgevolgd door onderstaande (mogelijk meer actuele) registratie
Geen registraties gevonden.
Andere (mogelijk minder actuele) registraties in dit register
Geen registraties gevonden.
In overige registers
| Register | ID |
|---|---|
| NTR-new | NL8897 |
| Ander register | MEC-U : W19.234 |