N/A
ID
Bron
Aandoening
Cystic Fibrosis
Primary Ciliary Dyskinesia
Ondersteuning
Academic Medical Centre, University of Amsterdam
Onderzoeksproduct en/of interventie
Uitkomstmaten
Primaire uitkomstmaten
1. Relative changes in electronic nose sensors;<br>
2. Retention time;<br>
3. Abundance and mass to charge ratio from GC-MS analysis.
Achtergrond van het onderzoek
N/A
Doel van het onderzoek
N/A
Onderzoeksopzet
3 monthly collection of study samples and during an exacerbation.
Onderzoeksproduct en/of interventie
Longitudinal observational study during one year with collection of 5 exhaled breath and microbiology samples.
Publiek
T. Paff
Department of pulmonology
VU University Medical Center, Amsterdam
Room PK 4X 023
Amsterdam 1007 MB
The Netherlands
+31 (0)20 4445491
t.paff@vumc.nl
Wetenschappelijk
T. Paff
Department of pulmonology
VU University Medical Center, Amsterdam
Room PK 4X 023
Amsterdam 1007 MB
The Netherlands
+31 (0)20 4445491
t.paff@vumc.nl
Belangrijkste voorwaarden om deel te mogen nemen (Inclusiecriteria)
1. CF diagnosis is based on: clinical symptoms in combination with an abnormal sweat test (chloride > 60 mmol/l) and/or identification of mutations in both alleles of the CFTR gene;
2. PCD diagnosis is based on: A combination of clinical symptoms, abnormal movement of cilia on microscopic evaluation of respiratory epithelial biopsies and epithelial cell cultures, or identification of an ultra structural defect in the cilia by electron microscopy;
3. ≥ 6 years of age;
4. Stable respiratory disease for at least 6 weeks ( as determined by the treating physician);
5. Ability to perform lung function measurement.
Belangrijkste redenen om niet deel te kunnen nemen (Exclusiecriteria)
1. Mental retardation;
2. Diabetes Mellitus (CF complication);
3. Technical unsatisfactory performance of measurements;
4. On the waiting list for lung transplantation;
5. Participation in the PREVEC or VERTEX study (AMC).
Opzet
Deelname
Opgevolgd door onderstaande (mogelijk meer actuele) registratie
Geen registraties gevonden.
Andere (mogelijk minder actuele) registraties in dit register
Geen registraties gevonden.
In overige registers
| Register | ID |
|---|---|
| NTR-new | NL3464 |
| NTR-old | NTR3616 |
| Ander register | : |
| ISRCTN | ISRCTN wordt niet meer aangevraagd. |