Thromboelastometry-based Assessment of Coagulation In Aortic Dissection

The aim of the present retrospective and prospective data collection is to estimate the incidence and degree of perioperative coagulation abnormalities using thromboelastometry (with both ROTEM® Delta and ROTEM® Sigma) as well as transfusion and coagulation factor requirements in patients undergoing aortic surgery (emergency and elective). We will collect data on patients scheduled for emergency surgery, due to acute type A aortic dissection and patients undergoing elective surgery of the aorta. Furthermore, we will compare the results from viscoelastic testing using ROTEM® Delta with ROTEM® Sigma.
The findings may help to optimize coagulation management in patients undergoing major aortic surgery, in order to minimize bleeding as well as thromboembolic complications, both of which can have devastating consequences in this high-risk patient population.

The aim of the present retrospective and prospective data collection is to estimate the incidence and degree of perioperative coagulation abnormalities, using thromboelastometry (with both ROTEM® Delta and ROTEM® Sigma), as well as transfusion and coagulation factor requirements, in patients undergoing elective and emergency aortic surgery.

All available perioperative timepoints: T0 = Baseline (before aortic cross-clamp), T1 = after aortic cross-clamp, T2 = admission to ICU, T3 = post-op day 1 ICU, T4,5= (optional) daily on ICU until discharge from ICU, T6 = 30 day follow-up for morbidity and mortality

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