Optimum timing of surgery for macula off rhegmatogenous retinal detachment can be determined in more detail by taking both duration and height of macular detachment into account.
ID
Bron
Verkorte titel
Aandoening
Rhegmatogenous retinal detachment is an ocular condition in which the neuroretina has detached from the underlying retinal pigment epithelium. This may result in lasting problems with visual function, even if the retina becomes reattached through surgery. Problems may include reduced visual acuity, metamorphopsia, and reduced contrast acuity. These problems occur more frequently when the centre of the retina, the macula, is involved in the detachment.
Ondersteuning
Onderzoeksproduct en/of interventie
Uitkomstmaten
Primaire uitkomstmaten
1. Visual acuity in relation to duration and height of macular detachment;
2. Individual parameters relating to visual function, subjective contentness and morphology of the macula in relation to each other.
Primary study group:
Pre-operative and postoperative at 1, 3, 6 and 12 months.
Secundary study group:
Pre-operative and 1 year after the latest vitreoretinal surgery.
Achtergrond van het onderzoek
A rhegmatogenous retinal detachment is a condition that can severly affect visual function, in particular when the macula is involved in the detachment. Previous studies evaluated whether duration of macular detachment or height of macular detachment influenced postoperative visual prognosis. Both factors - taken separately - are of importance, however when looking at duration of macular detachment no significant differences in visual recovery were observed between eyes with macular detachment of 1 to 9 days. The present study will evaluate whether differences in visual recovery can be related more strictly to duration of macular detachment when the data are corrected for height of macular detachment. This may result in a recommendation to change current practice with regard to patient scheduling in vitreoretinal surgery for rhegmatogenous retinal detachment.
Doel van het onderzoek
Optimum timing of surgery for macula off rhegmatogenous retinal detachment can be determined in more detail by taking both duration and height of macular detachment into account.
Onderzoeksproduct en/of interventie
Vitreoretinal surgery according to current practice guidelines.
Publiek
Department of Ophthalmology,
P.O. Box 30.001
D. Croonen
Groningen
The Netherlands
+31 (0)50 3612510
d.croonen@ohk.umcg.nl
Wetenschappelijk
Department of Ophthalmology,
P.O. Box 30.001
D. Croonen
Groningen
The Netherlands
+31 (0)50 3612510
d.croonen@ohk.umcg.nl
Belangrijkste voorwaarden om deel te mogen nemen (Inclusiecriteria)
Primary study group:
1. Rhegmatogenous retinal detachment with macula off during 1 day to 6 weeks;
2. Retinal reattachment after one surgical intervention;
3. No redetachment during the study period (1 year).
Secondary study group:
same as primary study group, but more than one vitreoretinal surgical procedure is needed to obtain retinal attachment.
Belangrijkste redenen om niet deel te kunnen nemen (Exclusiecriteria)
1. Pre-existent ocular pathology in the study or fellow eye that significantly influences visual acuity;
2. History of retinal detachment in the study or fellow eye.
Opzet
Deelname
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Andere (mogelijk minder actuele) registraties in dit register
Geen registraties gevonden.
In overige registers
| Register | ID |
|---|---|
| NTR-new | NL826 |
| NTR-old | NTR839 |
| Ander register | : N/A |
| ISRCTN | ISRCTN76474643 |