We hypothesize that the deformation-volume loop will help to identify the consequences of aortic stenosis and the changes in functionality after aortic valve replacement (AVR)
ID
Bron
Aandoening
Aortic valve stenosis and aortic valve replacement
Ondersteuning
Onderzoeksproduct en/of interventie
Uitkomstmaten
Primaire uitkomstmaten
Characteristic differences between the strain-volume loops of patients with chronic severe aortic stenosis pre and post aortic valve replacements.
Achtergrond van het onderzoek
Recent technical developments allow monitoring of strain and volume using echocardiography. Using this information enables the production of an strain-volume loop. In this study we will investigate the relationship strain and volume in patients with aortic stenosis pre and post aortic valve replacement. We aim to asses the structural and functional changes caused by aortic stenosis and after aortic valve replacement.
Doel van het onderzoek
We hypothesize that the deformation-volume loop will help to identify the consequences of aortic stenosis and the changes in functionality after aortic valve replacement (AVR)
Onderzoeksopzet
na
Onderzoeksproduct en/of interventie
na
Publiek
Dick H.J. Thijssen
Nijmegen 6525 EX
The Netherlands
+31 (0)24 3614222
d.thijssen@fysiol.umcn.nl
Wetenschappelijk
Dick H.J. Thijssen
Nijmegen 6525 EX
The Netherlands
+31 (0)24 3614222
d.thijssen@fysiol.umcn.nl
Belangrijkste voorwaarden om deel te mogen nemen (Inclusiecriteria)
Chronic servere aortic stenosis for which aortic valve replacement is applied. Echographic assessment within 1 month after AVR and at leas 6 months after AVR
Belangrijkste redenen om niet deel te kunnen nemen (Exclusiecriteria)
- hypokinetich or akinetic cardiac wall segments due to a myocardiol infarction in the past.
- co-existing mitral, pulmonic or tricuspid valve disease
Opzet
Deelname
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In overige registers
| Register | ID |
|---|---|
| NTR-new | NL5650 |
| NTR-old | NTR5767 |
| Ander register | CMO regio Arnhem-Nijmegen : 2016-2357 |