A near-infrared fluorescence camera and a peritumoral injection of indocyanine green may be used for detection of lymph nodes during esophageal resections without affecting the normal operative procedure.
ID
Bron
Verkorte titel
Aandoening
Esophageal cancer
Ondersteuning
Hanzeplein 1
9700 RB Groningen
The Netherlands
Hanzeplein 1
9700 RB Groningen
The Netherlands
Onderzoeksproduct en/of interventie
Uitkomstmaten
Primaire uitkomstmaten
Application of the near-infrared fluorescence camera safely without disturbing the normal operative procedure.
Achtergrond van het onderzoek
The primary aim of the study is to assess whether our Near-Infrared
Fluorescence camera may safely be used during esophageal resections. The
secondary aim is the intraoperative detection of lymph nodes using
indocyanine green and a Near-Infrared Fluorescence camera.
Patients undergoing esophagectomy for cancer of the esophagus will
receive an intraoperative peritumoral injection with ICG. Imaging will
subsequently take place using the NIRF camera to assess whether lymph
nodes may be detected.
Doel van het onderzoek
A near-infrared fluorescence camera and a peritumoral injection of indocyanine green may be used for detection of lymph nodes during esophageal resections without affecting the normal operative procedure.
Onderzoeksopzet
N/A
Onderzoeksproduct en/of interventie
Peritumoral injection with indocyanine green and subsequent imaging using the intraoperative near-infrared fluorescence camera.
Publiek
Department of Surgery / BioOptical Imaging Center Groningen <br>
G.M. Dam, van
Hanzeplein 1
Groningen 9700 RB
The Netherlands
+31 (0)50 3612283
g.m.van.dam@chir.umcg.nl
Wetenschappelijk
Department of Surgery / BioOptical Imaging Center Groningen <br>
G.M. Dam, van
Hanzeplein 1
Groningen 9700 RB
The Netherlands
+31 (0)50 3612283
g.m.van.dam@chir.umcg.nl
Belangrijkste voorwaarden om deel te mogen nemen (Inclusiecriteria)
Men and women above the age of 21 who have biopsy-proven esophageal cancer that is deemed operable by the treating surgeon by the current staging protocol at the UMCG (i.e. endoscopy, endo ultrasound, CT thorax/abdomen, PET scan).
Belangrijkste redenen om niet deel te kunnen nemen (Exclusiecriteria)
1. Significant renal, cardiac, or pulmonary disease (ASA III-IV);
2. History of iodine allergy or anaphylactic reactions to insect bites or medication;
3. Presence or history of hyperthyroidism.
Opzet
Deelname
Opgevolgd door onderstaande (mogelijk meer actuele) registratie
Geen registraties gevonden.
Andere (mogelijk minder actuele) registraties in dit register
Geen registraties gevonden.
In overige registers
| Register | ID |
|---|---|
| NTR-new | NL1889 |
| NTR-old | NTR2003 |
| Ander register | UMCG : BICG08UMCG-NIRF |
| ISRCTN | ISRCTN wordt niet meer aangevraagd. |