Psoas Compartment - Sciatic Nerve Block, as an adjuvant locoregional anesthetic technique, gives sufficient post operative pain reduction after total hip replacement, regardless which long acting local anesthetic ((levo)bupivacaine or ropivacaine in…
ID
Bron
Verkorte titel
Aandoening
1. Total Hip Replacement (NLD: Totale Heup Prothese);
2. Psoas Compartment Block;
3. Sciatic Nerve Block (NLD: Nervus Ischiadicus Blokkade).
Ondersteuning
Onderzoeksproduct en/of interventie
Uitkomstmaten
Primaire uitkomstmaten
Pain (Visual Analog Scale) op T = 4,8,12,24,48 hour post - puncture.
Achtergrond van het onderzoek
Aim of our study is to compare postoperative analgesic efficacy, and the extent of sensory and motor blockade of levobupivacaine, ropivacaine and bupivacaine administered in a combined psoas compartment – sciatic nerve block (PCSNB) for total hip replacement.
45 patients undergoing total hip replacement under general anesthesia combined with PCSNB, were randomly assigned to receive either 50 cc levobupivacaine 3 mg/ml, 50 cc ropivacaine 4.5 mg/ml or 50 cc bupivacaine 3 mg/ml with epinephrine. Postoperative, the pain intensity at rest (VAS), the degree of motor block (modified Bromage Scale) and the extent of sensory block (pin prick test) will be recorded at 4, 8, 12, 24 and 48 hours following initial injection in a double blind fashion.
Doel van het onderzoek
Psoas Compartment - Sciatic Nerve Block, as an adjuvant locoregional anesthetic technique, gives sufficient post operative pain reduction after total hip replacement, regardless which long acting local anesthetic ((levo)bupivacaine or ropivacaine in equipotent dosages) is used.
Onderzoeksopzet
N/A
Onderzoeksproduct en/of interventie
Psoas Compartment - Sciatic Nerve Block given with Bupivacaine, Levobupivacaine or Ropivacaine. Duration of the intervention: 10 min.
Publiek
postbus 7057
Roberto S.G.M. Perez
Amsterdam 1007 MB
The Netherlands
+31 20-4440029.
rsgm.perez@vumc.nl
Wetenschappelijk
postbus 7057
Roberto S.G.M. Perez
Amsterdam 1007 MB
The Netherlands
+31 20-4440029.
rsgm.perez@vumc.nl
Belangrijkste voorwaarden om deel te mogen nemen (Inclusiecriteria)
1. Age above 18;
2. ASA classification I-III;
3. Total Hip Replacement under general anesthesia.
Belangrijkste redenen om niet deel te kunnen nemen (Exclusiecriteria)
1. Co-agulation disorders;
2. Infections at puncture sites;
3. Known allergy to local anesthetics;
4. Pre-existing neurological dysfunction;
5. Not been able to proper communication.
Opzet
Deelname
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In overige registers
Register | ID |
---|---|
NTR-new | NL964 |
NTR-old | NTR990 |
Ander register | : |
ISRCTN | ISRCTN16416351 |