The overall hypothesis is that balance-specific exercise training only improves postural control of sway measured in standing and causes retention of the improved sway behavior and that such behavioral improvements correlate with changes in measures…
ID
Bron
Aandoening
Aging
Ondersteuning
Onderzoeksproduct en/of interventie
Uitkomstmaten
Primaire uitkomstmaten
Behavioral outcome during balance learning is the error produced by balancing on an unstable balance board (Sensamove, Groessen, NL). The error, in degrees, is computed as the cumulative deviation between the position of the board relative to the horizontal. In addition to the performance on the balance board, the laboratory behavioral outcome is the magnitude of sway on the force platform measured in standing with a narrow stance during TMS and EEG testing. Magnitude of sway is expressed in cm as path length over unit time and the velocity of sway in the anterior-posterior and in the medio- lateral directions.
Doel van het onderzoek
The overall hypothesis is that balance-specific exercise training only improves postural control of sway measured in standing and causes retention of the improved sway behavior and that such behavioral improvements correlate with changes in measures of neuronal excitability in the brain.
Onderzoeksopzet
acute study: week 1
Chronic study: week 1, week 4 and week 6
Onderzoeksproduct en/of interventie
Balance training on an unstable surface, cycling on an a stationary bicycle ergometer and no-intervention control
Publiek
Wetenschappelijk
Belangrijkste voorwaarden om deel te mogen nemen (Inclusiecriteria)
Young adults: Age between 18 and 40, female or male, healthy.
Old adults: Age between 65 and 85, female or male, healthy.
Belangrijkste redenen om niet deel te kunnen nemen (Exclusiecriteria)
A score lower than 24 on the Mini Mental State Examination
A score higher than 70 on the falls self-efficacy scale
More than 1 fall over the past year (‘Coming unintentionally to rest on the ground, floor, or lower level’)
Do not meet TMS guidelines
Unable to stand independently for 10 minutes without rest
Epilepsy
Any metal in the brain/skull
Electrical, magnetic, or mechanical implantation: cardiac pacemakers or intracerebral vascular clip
Pregnancy or suspicion of pregnancy
History of seizures or unexplained loss of consciousness
Immediate family member with epilepsy
Use of seizure threshold lowering medicine
History of Schizophrenia
History of Hallucinations
History of other neurological disorders
A prior stroke, heart attack, heart failure, bypass, cardiac arhythmia Acute flu or cold
Spinal, joint, and head pain
Diabetes mellitus
Hypertension (systolic/diastolic > 160/ > 100 mmHg)
Acute and chronic inflammatory condition
Severe arthrosis
Vertigo
Knee or hip endoprosthesis
Trauma within the last 6 months
Active cancer, cancer therapy
Opzet
Deelname
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In overige registers
| Register | ID |
|---|---|
| NTR-new | NL6691 |
| NTR-old | NTR6861 |
| Ander register | NL64147.041.17 : 201700861 |