Children with Osteogenesis Imperfecta type I and IV would benefit from a gradual trainingsprogram; increased exercise capacity and muscle strength could increase quality of life.
ID
Bron
Verkorte titel
Aandoening
Osteogenesis Imperfecta type I and IV.
Ondersteuning
KB 02.056.0
Lundlaan 6
3584 EA
P.O. box 85090
3508 AB Utrecht
Tel +32302504030
Fax +32302505333
m.vanbrussel@umcutrecht.nl
Onderzoeksproduct en/of interventie
Uitkomstmaten
Primaire uitkomstmaten
Exercise capacity and muscle strength.
Achtergrond van het onderzoek
Aim of this study is to investigate if children with Osteogenesis Imperfecta between 8 and 18 years of age benefit from a graded exercise program with respect to exercise capacity, muscle strength, functional outcome and quality of life. thirthy-eight children with OI type I and IV between 8 and 18 years of age will be randomly assigned in two groups (RCT). eightteen children will be treated with a graded exercise protocol, by trained paediatric physical therapists, whereas the control group will not be treated and serve as the control group.
Doel van het onderzoek
Children with Osteogenesis Imperfecta type I and IV would benefit from a gradual trainingsprogram; increased exercise capacity and muscle strength could increase quality of life.
Onderzoeksopzet
N/A
Onderzoeksproduct en/of interventie
Training program for 12 weeks (2 times/ week).
Publiek
P.O. box 85090
R.H.H. Engelbert
Lundlaan 6
Utrecht 3508 AB
The Netherlands
+31 (0)30 2504030
r.engelbert@umcutrecht.nl
Wetenschappelijk
P.O. box 85090
R.H.H. Engelbert
Lundlaan 6
Utrecht 3508 AB
The Netherlands
+31 (0)30 2504030
r.engelbert@umcutrecht.nl
Belangrijkste voorwaarden om deel te mogen nemen (Inclusiecriteria)
1. Osteogenesis Imperfecta Type I and IV;
2. between 8 and 18 years of age;
3. ambulantory.
Belangrijkste redenen om niet deel te kunnen nemen (Exclusiecriteria)
1. Osteogenesis Imperfecta type II and III;
2. retardation;
3. non-walking.
Opzet
Deelname
Opgevolgd door onderstaande (mogelijk meer actuele) registratie
Geen registraties gevonden.
Andere (mogelijk minder actuele) registraties in dit register
Geen registraties gevonden.
In overige registers
| Register | ID |
|---|---|
| NTR-new | NL87 |
| NTR-old | NTR118 |
| Ander register | : 04/331-k (METC UMCU) |
| ISRCTN | ISRCTN28577651 |
Samenvatting resultaten
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2. Takken T, Terlingen HC, Helders PJ, Pruijs H, Van der Ent CK, Engelbert RH. Cardiopulmonary fitness and muscle strength in patients with osteogenesis imperfecta type I.J Pediatr. 2004 Dec;145(6):813-8.<br>