We hypothesize that the greater part of professional cyclist will be diagnosed with osteopenia or osteoporosis. Furthermore, we expect that low bone mineral density will not be normalized after the active career.
ID
Bron
Verkorte titel
Aandoening
Osteoporosis
Ondersteuning
Onderzoeksproduct en/of interventie
Uitkomstmaten
Primaire uitkomstmaten
Whole body and regional (lumbar spine and femoral hip) bone mineral density (t- and z-scores) and bone mineral content as determined by dual-energy X-ray absorptiometry (DXA).
Achtergrond van het onderzoek
Bone is a highly dynamic tissue that undergoes constant remodeling, mainly influenced by physical activity. Non-weight-bearing activities, such as cycling do not contribute to bone health, with potentially severe consequences for individuals who engage in high volume non-weight-baring exercise training and competition such as professional cyclists. There is a lack of data on the time course and severity of low bone mineral density in professional and retired cyclists. We hypothesize that the greater part of professional cyclist will be diagnosed with osteopenia or osteoporosis. Furthermore, we expect that low bone mineral density will not be normalized after the active career.
Doel van het onderzoek
We hypothesize that the greater part of professional cyclist will be diagnosed with osteopenia or osteoporosis. Furthermore, we expect that low bone mineral density will not be normalized after the active career.
Onderzoeksopzet
A subgroup of young talented cyclists will be followed over a 4 year period, including yearly measurements of bone mineral density during the off-season.
Onderzoeksproduct en/of interventie
None
Publiek
Wetenschappelijk
Belangrijkste voorwaarden om deel te mogen nemen (Inclusiecriteria)
Inclusion criteria
World tour level (highest level) professional male cyclists (aged 22 – 40):
• Male
• Professional cyclist competing in UCI’s WorldTour competition
• Willing to give written informed consent.
• Willing to comply with study procedures.
• Accept use of all encoded data, including publication, and the confidential use and storage of all data for 15 years.
World tour level professional female cyclists (aged 22 – 40):
• Female
• Professional cyclist competing in UCI’s Women’s WorldTour competition
• Willing to give written informed consent.
• Willing to comply with study procedures.
• Accept use of all encoded data, including publication, and the confidential use and storage of all data for 15 years.
Talented elite male cyclist (aged 18 – 22):
• Male
• Included in a talent program of professional cycling team
• Willing to give written informed consent.
• Willing to comply with study procedures.
• Accept use of all encoded data, including publication, and the confidential use and storage of all data for 15 years.
Retired world tour level professional cyclists (aged 35 – 60):
• Retired male of female professional cyclist.
• A minimum of 5 years of professional cycling at WorldTour level.
• Duration of retirement is minimal 1 year before Day 01 of this study.
• Willing to give written informed consent.
• Willing to comply with study procedures.
• Accept use of all encoded data, including publication, and the confidential use and storage of all data for 15 years.
Belangrijkste redenen om niet deel te kunnen nemen (Exclusiecriteria)
Exclusion criteria
• Having a history of medical events or medication use that may significantly affect bone metabolism, to be decided by the principal investigator.
• Medication use that may affect tests within this study must be minimal 3 months before Day 01 of this study.
• Participation in any clinical trial including blood sampling and/or administration of substances up to 30 days before Day 01 of this study
• A recent injury that may significantly affect BMD, to be decided by the principal investigator.
Opzet
Deelname
Voornemen beschikbaar stellen Individuele Patiënten Data (IPD)
Toelichting
Opgevolgd door onderstaande (mogelijk meer actuele) registratie
Geen registraties gevonden.
Andere (mogelijk minder actuele) registraties in dit register
Geen registraties gevonden.
In overige registers
| Register | ID |
|---|---|
| NTR-new | NL8691 |
| Ander register | METC Zuyderland : METCZ20200039 |