Currently, the effects of nutrition or specific food components, including those on absorption or metabolism, are mostly studied via parameters in blood samples. To reduce the burden for participants of nutritional intervention studies, there is a…
ID
Bron
Aandoening
breath, exhaled air, VOC (volatile organic compound), lipid metabolism, fat
Ondersteuning
Onderzoeksproduct en/of interventie
Uitkomstmaten
Primaire uitkomstmaten
postprandial change in VOCs (volatile organic compounds) in exhaled air
Achtergrond van het onderzoek
Exhaled air contains large numbers of volatile organic compounds (VOCs) that may be derived from the body's internal metabolism. The main ovjective of this study is to investigate whether it is possible to use VOCs in exhaled air as a parameter of lipid metabolism.
Doel van het onderzoek
Currently, the effects of nutrition or specific food components, including those on absorption or metabolism, are mostly studied via parameters in blood samples. To reduce the burden for participants of nutritional intervention studies, there is a high need for non-invasive methods. Exhaled air contains large numbers of volatile organic compounds (VOCs) that may be derived from the body's internal metabolism. So this might be an interesting, non-invasive parameter.
Onderzoeksopzet
various measurements for 5 hours postprandial
Onderzoeksproduct en/of interventie
low-fat milk (0.1% fat) vs high-fat milk (10% fat)
Publiek
Wetenschappelijk
Belangrijkste voorwaarden om deel te mogen nemen (Inclusiecriteria)
- Caucasian male
- 18-35 years old
- Body mass index between 22-25 kg/m2
- Fat percentage between 8-15%
- Regular consumption of milk (products)
Belangrijkste redenen om niet deel te kunnen nemen (Exclusiecriteria)
- (symptoms of) cow's milk allergy
- lactose intolerance
- metabolic diseases
- (known symptoms of) (auto)immune diseases, like diabetes
- (known symptoms of) intestinal diseases, like: irritable bowel syndrome, intestinal malabsorption, diagnosed with celiac disease, Chron's disease, coliltis ulcerosa, short bowel syndrome or surgical bowel interventions leading to malabsorption
- usage of medication
- usage or hard drugs
- history of smoking
- claustrophobia
- unsuitable veins for blood sampling
- blood donation during the two months before the start of the study
- current participation in other scientific studies
Opzet
Deelname
Opgevolgd door onderstaande (mogelijk meer actuele) registratie
Geen registraties gevonden.
Andere (mogelijk minder actuele) registraties in dit register
Geen registraties gevonden.
In overige registers
| Register | ID |
|---|---|
| NTR-new | NL5819 |
| NTR-old | NTR5974 |
| Ander register | METC WUR : 16/05 |