Preterm infants have a reduced length and bone density in later life compared to peers born at term. In our study we want to determine if preterm infants with different intake of calcium and phosphate in the neonatal period, have a difference in…
ID
Bron
Verkorte titel
Aandoening
FoBoMin
preterm infants
bone mineralization
length
Ondersteuning
Onderzoeksproduct en/of interventie
Uitkomstmaten
Primaire uitkomstmaten
To determine whether increased calcium and phosphate intake (2005 group) resulted in improved Bone mineral content (BMC) and Bone mineral density (BMD) compared to the group with less calcium and phosphate intake (2004 group) at the age of 8-10 years, determined by DEXA-scan.
Doel van het onderzoek
Preterm infants have a reduced length and bone density in later life compared to peers born at term.
In our study we want to determine if preterm infants with different intake of calcium and phosphate in the neonatal period, have a difference in bone mineralization and length at the age of 8-10 years.
We hypothesize that the former preterm infants, with higher intake of calcium and phosphate have an improved bone mineralization and length compared to the preterm infants with less intake of calcium and phosphate.
Onderzoeksopzet
just one outpatient visit
Onderzoeksproduct en/of interventie
- Questionnaire
- Anthropometric measurements
- Quantitative ultrasound
- DEXA-scan
Publiek
Postbus 9101
M.E. Putten, van der
Nijmegen 6500 HB
The Netherlands
+31 24 3614430
Mayke.vanderPutten@radboudumc.nl
Wetenschappelijk
Postbus 9101
M.E. Putten, van der
Nijmegen 6500 HB
The Netherlands
+31 24 3614430
Mayke.vanderPutten@radboudumc.nl
Belangrijkste voorwaarden om deel te mogen nemen (Inclusiecriteria)
The children who were included in a former cohort study were born during the year 2004 (68 children with the old composition of parenteral feeding) and 2005 (79 children with the new composition of parenteral feeding). They had at birth a gestational aged below 34 weeks, were admitted to our NICU of the first day of life and had an expected duration of parenteral nutrition of more than five days.
Of these former cohorts 55 respectively 60 children were seen at the follow-up at two years and these children we have invited for the current FoBoMin study.
Belangrijkste redenen om niet deel te kunnen nemen (Exclusiecriteria)
- Asphyxia
- Congenital malformation
- Renal or hepatic insufficiency at birth
- No follow up at 2 years of age
Opzet
Deelname
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In overige registers
| Register | ID |
|---|---|
| NTR-new | NL4413 |
| NTR-old | NTR4842 |
| Ander register | METC : 2013/594 |