We expect to find a large heterogeneity in transfusion practice (i.e. thresholds and motivation for transfusion) in ICUs worldwide.
ID
Bron
Verkorte titel
Aandoening
All patients ≥ 18 years admitted to the adult Intensive Care Unit.
Ondersteuning
Onderzoeksproduct en/of interventie
Uitkomstmaten
Primaire uitkomstmaten
Our objective is to quantify international transfusion practice in ICUs. We will be looking at transfusion and administration of RBCs, platelets, plasma and several coagulation agents (pro-coagulant and anti-fibrinolytic) in correlation to clinical parameters and corresponding laboratory values. Differences within and between regions will be studied.
Achtergrond van het onderzoek
It has been known that the variance in transfusion practice in intensive care units (ICUs) is high worldwide. However, current studies are limited among others by focusing on one blood product or one country’s practice. This point prevalence study aims to describe transfusion practice in an observational point prevalence design in ICUs worldwide. Moreover, we aim to describe the physiological triggers and clinician’s motivation for transfusion.
Doel van het onderzoek
We expect to find a large heterogeneity in transfusion practice (i.e. thresholds and motivation for transfusion) in ICUs worldwide.
Onderzoeksopzet
Each center signs up for an inclusion week. In every inclusion week, for every newly admitted patient of >18 years and older, several questionnaires need to be filled in:
- Baseline demographics;
- Daily questionnaire up to 28 days or ICU discharge, whatever comes first;
- Outcome questionnaire;
- For every transfusion a separate transfusion questionnaire.
Publiek
Wetenschappelijk
Belangrijkste voorwaarden om deel te mogen nemen (Inclusiecriteria)
Patients are included in the study if they are aged 18 years and older and are newly admitted to the ICU during the course of a pre-specified week (7 days).
Belangrijkste redenen om niet deel te kunnen nemen (Exclusiecriteria)
All patients younger than 18 years old
No informed consent in countries where no opt-out procedure applies.
Opzet
Deelname
Voornemen beschikbaar stellen Individuele Patiënten Data (IPD)
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In overige registers
| Register | ID |
|---|---|
| NTR-new | NL9049 |
| Ander register | METC AMC : W18_290#18.449 |