Affective disorders, encompassing unipolar depressive disorders, anxiety disorders and somatic symptom disorders, are the most prevalent psychiatric disorders in later life. Treatment protocols and guidelines largely rely on randomized controlled…
ID
Bron
Verkorte titel
Aandoening
Depressive disorders (i.e. major depressive disorder, persistent depressive disorder, minor depressive disorder), anxiety disorders (i.e. panic disorder, agoraphobia, social anxiety disorder, generalized anxiety disorder), and somatic symptom disorders (i.e. somatic symptom disorder, illness anxiety disorder)
Keywords: depressive disorders, anxiety disorders, somatic symptom disorders, geriatric mental health care, cohort study, routine outcome monitoring
Trefwoorden: stemmingsstoornissen, angststoornissen, somatisch symptoom stoornissen, ouderenpsychiatrie, cohort studie, routine outcome monitoring
Ondersteuning
University Medical Center Groningen
The Netherlands
Onderzoeksproduct en/of interventie
Uitkomstmaten
Primaire uitkomstmaten
The primary outcome is remission of the index affective disorder at one-year follow-up or end of treatment (if earlier)
Achtergrond van het onderzoek
Background – Affective disorders, encompassing unipolar depressive disorders, anxiety disorders and somatic symptom disorders, are the most prevalent psychiatric disorders in later life. Treatment protocols and guidelines largely rely on randomized controlled trials conducted in younger age samples. Moreover, studies in geriatric psychiatry are often limited to the “younger olds” and rarely include frail of cognitive impaired older adults. Therefore, the impact of ageing characteristics on the effectiveness of treatment in routine clinical care for older patients is largely unknown.
Objective - The primary aim of the Routine Outcome Monitoring for Geriatric Psychiatry & Science (ROM-GPS) is to examine the impact of ageing characteristics on the effectiveness of routinely delivered psychiatric care in specialised mental health care for older patients with affective disorders.
Methods – ROM-GPS is a two-stage project, screening all patients referred to one the participating outpatient clinics for specialised mental health care with the Mini International Neuropsychiatric Interview and some symptom severity scales. Patients with a depressive, anxiety or somatic symptom disorder will be asked informed consent and extensively phenotyped at baseline and closely monitored during their first year of treatment. In addition to a large test battery of potential confounders, specific attention is paid to cognitive functioning (including computerized tests with the cogstate test battery as well as paper and pencil test) and physical functioning (including multimorbidity, polypharmacy, the physical frailty phenotype as well as the much broader Tilburgse Frailty indicator).
Doel van het onderzoek
Affective disorders, encompassing unipolar depressive disorders, anxiety disorders and somatic symptom disorders, are the most prevalent psychiatric disorders in later life. Treatment protocols and guidelines largely rely on randomized controlled trials conducted in younger age samples. Moreover, studies in geriatric psychiatry are often limited to the “younger olds” and rarely include frail of cognitive impaired older adults. Therefore, the impact of ageing characteristics on the effectiveness of treatment in routine clinical care for older patients is largely unknown.
The primary aim of the Routine Outcome Monitoring for Geriatric Psychiatry & Science (ROM-GPS) is to examine the impact of ageing characteristics on the effectiveness of routinely delivered psychiatric care in specialised mental health care for older patients with affective disorders.
Onderzoeksopzet
Timepoints are: screening and baseline assessment (if included) at intake in outpatient mental health care, four-monthly postal questionnaires during treatment, one-year follow-up assessment (or at end of treatment if earlier), and two-year follow-up assessment.
Onderzoeksproduct en/of interventie
Routinely provided treatments in outpatient geriatric mental health care are registered
Publiek
for Mental Health Services Research
Department of Psychiatry
University Medical Center Groningen
P.O. Box 30.001
Rob Brink, van den
Groningen 9700 RB
The Netherlands
+31 50 3612089
r.h.s.van.den.brink@med.umcg.nl
Wetenschappelijk
for Mental Health Services Research
Department of Psychiatry
University Medical Center Groningen
P.O. Box 30.001
Rob Brink, van den
Groningen 9700 RB
The Netherlands
+31 50 3612089
r.h.s.van.den.brink@med.umcg.nl
Belangrijkste voorwaarden om deel te mogen nemen (Inclusiecriteria)
Inclusion criteria are 1) 60 years or older, 2) referred to one the participating outpatient clinics for specialised mental health care, 3) presence of an affective disorder confirmed by the Mini International Neuropsychiatric Interview-Plus (MINI-Plus), and 4) given informed consent.
Belangrijkste redenen om niet deel te kunnen nemen (Exclusiecriteria)
Exclusion criteria are 1) an established diagnosis of a neurodegenerative disorder or less than 18 points on the Montreal Cognitive Assessment (MoCA) test, 2) a (history of a) bipolar or psychotic disorder, 3) a severe substance-use disorder in need of specialised treatment, 4) physically or mentally too handicapped to administer self-report questionnaires or perform cognitive testing, or 5) insufficient mastery of the Dutch language.
Opzet
Deelname
Opgevolgd door onderstaande (mogelijk meer actuele) registratie
Geen registraties gevonden.
Andere (mogelijk minder actuele) registraties in dit register
Geen registraties gevonden.
In overige registers
| Register | ID |
|---|---|
| NTR-new | NL6704 |
| NTR-old | NTR6874 |
| CCMO | NL47717.042.14 |