The primary objective is to set up a pilot sentinel syndromic surveillance system for patients with a severe acute respiratory infection (SARI) requiring hospital admission
ID
Bron
Verkorte titel
Aandoening
severe acute respiratory infection, surveillance, influenza, hospital admission, ernstige acute luchtweg infectie, ziekenhuisopname, SARI
Ondersteuning
Onderzoeksproduct en/of interventie
Uitkomstmaten
Primaire uitkomstmaten
The development and establishment of a sustainable SARI surveillance system that, when this is proven feasible, will be extended to other hospitals from the year 2019 onward. The end result is an integrated respiratory surveillance system covering the full spectrum of respiratory infections, which provides input for (inter)national public administrations and is used for policy decisions.<br>
The planned products are:<br>
•Protocol for the implementation of a potential nationwide sustainable continuous SARI surveillance; <br>
•Weekly publication of the results of fully integrated respiratory surveillance system on RIVM website.
Achtergrond van het onderzoek
Surveillance of respiratory infections in primary care in the Netherlands was established more than 40 years ago. The registration of influenza-like illness by general practitioners, complemented by virological analysis of nasal/
throat swabs, represent the current base of the surveillance pyramid of respiratory infections in the Netherlands. The missing link between primary care and crude mortality monitoring is the surveillance of patients with severe
acute respiratory infections (SARI) requiring hospital admission. A sustained SARI surveillance system detects outbreaks in time, place, causative pathogen and person in order to implement and evaluate health care interventions. Several other countries have implemented an operative SARI surveillance system as advised by the World Health
Organization (WHO). From October 2015 onwards, a pilot study started at the Jeroen Bosch Hospital and Leiden University Medical Center with the main objective to
set up a sentinel surveillance system for SARI patients in the Netherlands. However, adding laboratory diagnostic results is crucially important and should result in a sustained integrated respiratory surveillance system in the future.
Doel van het onderzoek
The primary objective is to set up a pilot sentinel syndromic surveillance system for patients with a severe acute respiratory infection (SARI) requiring hospital admission
Onderzoeksopzet
Within the whole study period, important timepoints are:
•influenza season 2015-2016
•influenza season 2016-2017
•influenza season 2017-2018
Onderzoeksproduct en/of interventie
This is not an intervention study
Publiek
Centre for Infectious disease control (CIb)
National Institute for public health and the Environment (RIVM)
Sierk Marbus
PO Box 1
Bilthoven 3720 BA
The Netherlands
T +31 (0)302742045
sierk.marbus@rivm.nl
Wetenschappelijk
Centre for Infectious disease control (CIb)
National Institute for public health and the Environment (RIVM)
Sierk Marbus
PO Box 1
Bilthoven 3720 BA
The Netherlands
T +31 (0)302742045
sierk.marbus@rivm.nl
Belangrijkste voorwaarden om deel te mogen nemen (Inclusiecriteria)
A SARI patient will be defined as a hospitalised person with:
•at least one systemic symptom or sign: fever or feverishness, malaise, headache or myalgia or deterioration of general condition (asthenia or loss of weight or anorexia or confusion or dizziness)
v
and
•at least one respiratory symptom or sign (cough, sore throat or shortness of breath)
at admission or within 48 hours after admission.
Belangrijkste redenen om niet deel te kunnen nemen (Exclusiecriteria)
The symptoms of onset should not have started (or clearly worsened, if chronic) more than 7 days at admission
Opzet
Deelname
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In overige registers
| Register | ID |
|---|---|
| NTR-new | NL5891 |
| NTR-old | NTR6079 |
| Ander register | METC UMC Utrecht : 15-483/C |