Perioperative fluid expansion as primairy treatment of hypotension in day case surgery leads to a modest increase of cardiac output.
ID
Bron
Verkorte titel
Aandoening
Cardiac output
Nexfin
General anesthesia
Day case sugery
Fluid expansion
Ondersteuning
Onderzoeksproduct en/of interventie
Uitkomstmaten
Primaire uitkomstmaten
Cardiac output before and after fluid expansion.
Achtergrond van het onderzoek
Fluid expansion is considered the primary intervention in case of hypotension during general anesthesia. The aim of this study is to determine the efficacy of fluid expansion in the treatment of hyotension during day case surgery in patients under general anesthesia without significant blood loss. Fluid expansion of 6 ml/kg ideal weight is administered in case of hypotension, defined as systolic blood pressure < 90 mHg or a decrease in mean arterial pressure of > 25%. The effect of fluid expansion on cardiac output and blood pressure is measured using Nexfin, a non-invasive continuous cardiac output monitor.
Doel van het onderzoek
Perioperative fluid expansion as primairy treatment of hypotension in day case surgery leads to a modest increase of cardiac output.
Onderzoeksopzet
T0= Before start of fluid expansion;
T1= 5 minutes after completion of fluid expansion;
T2= 20 minutes after fluid expansion;
T3=30 minutes after fluid expansion.
Onderzoeksproduct en/of interventie
Fluid expansion of 6 ml/kg ideal weight in case of hypotension, defined as systolic blood pressure < 90 mHg or a decrease in mean arterial pressure of > 25%.
Publiek
Charlotte Hofhuizen
Nijmegen 6525 GA
The Netherlands
+31 (0)24 3614406
c.hofhuizen@anes.umcn.nl
Wetenschappelijk
Charlotte Hofhuizen
Nijmegen 6525 GA
The Netherlands
+31 (0)24 3614406
c.hofhuizen@anes.umcn.nl
Belangrijkste voorwaarden om deel te mogen nemen (Inclusiecriteria)
1. Patients under general anesthesia in minor day case sugery;
2. ASA classification I and II.
Belangrijkste redenen om niet deel te kunnen nemen (Exclusiecriteria)
1. Age < 18 years;
2. Duration of surgery > 240 minutes;
3. Digital ischaemia;
4. Preexisting cardiac arrhythmias;
5. Expected blood loss > 300 ml
Opzet
Deelname
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