Null hypothesis: sublingual immunotherapy with house dust mite allergen is as effective as placebo on daily symptoms in children with allergic rhinitis.
ID
Bron
Verkorte titel
Aandoening
allergic rhinitis related to house dust mite allergy
Ondersteuning
Onderzoeksproduct en/of interventie
Uitkomstmaten
Primaire uitkomstmaten
Mean rhinitis symptom score in September-December after 2 years of SLIT / placebo.
Achtergrond van het onderzoek
N/A
Doel van het onderzoek
Null hypothesis: sublingual immunotherapy with house dust mite allergen is as effective as placebo on daily symptoms in children with allergic rhinitis.
Onderzoeksproduct en/of interventie
Sublingual immunotherapy (SLIT) with house dust mite allergen during 24-26 months.
Publiek
P.O. Box 1738
H. Moed
Molewaterplein 40
Rotterdam 3000 DR
The Netherlands
+31 (0)10 4088194
h.moed@erasmusmc.nl
Wetenschappelijk
P.O. Box 1738
H. Moed
Molewaterplein 40
Rotterdam 3000 DR
The Netherlands
+31 (0)10 4088194
h.moed@erasmusmc.nl
Belangrijkste voorwaarden om deel te mogen nemen (Inclusiecriteria)
1. Age: 6-18 years;
2. History of allergic rhinitis for at least one year;
3. Positive RAST for house dust mite allergy (¡Ý2+);
4. No use of nasal steroids in month before start of baseline measurements;
5. Symptom score of at least 4/12 (four nasal symptoms with scores ranging 0-3);
6. Informed consent.
Belangrijkste redenen om niet deel te kunnen nemen (Exclusiecriteria)
1. Severe asthma;
2. Allergic sensitivity to pets, in case these are present in the family home;
3. Planned surgery of nasal cavity in the course of the study;
4. Having received immunotherapy in past three years;
5. Contraindications to sublingual immunotherapy.
Opzet
Deelname
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Andere (mogelijk minder actuele) registraties in dit register
Geen registraties gevonden.
In overige registers
| Register | ID |
|---|---|
| NTR-new | NL346 |
| NTR-old | NTR385 |
| Ander register | : N/A |
| ISRCTN | ISRCTN91141483 |