Congenital Cytomegaly Virus Infection: correlation of Fetal MRI findings vs clinical outcome

The aim of the study is to improve the prenatal counselling of parents and to guide future management decisions in cases of proven cCMV infection. In particular the emphasis is on the additional contribution made by in utero MRI relative to the information already established by antenatal ultrasound, timing of CMV infection. In order to achieve this, the following measures will be analysed:

- Comparison of the diagnostic agreement between antenatal ultrasound and in utero MRI

- Quantification of the diagnostic accuracy of MRI in cases of proven cCMV infection (with reference to clinical and pathological outcome)

- Correlation of MRI findings with clinical outcome.

- Comparison between the first MRI diagnosis at the first center and the second look by a trained fetal MRI specialist.

Fetal MRI can be helpfull in detecting CMV related lesions and can help in this way the counseling of patients in the future.

1 MRI during pregnancy
at least 1 clinical follow up postnataland/or autopsy findings.

second look fetal MRI + correlation postnatal follow up