Serum testosterone levels in men will be related to basic cognitive functions, such as mental processing speed and cognitive control.
ID
Bron
Verkorte titel
Aandoening
BPH or fertility problems
Ondersteuning
Onderzoeksproduct en/of interventie
Uitkomstmaten
Primaire uitkomstmaten
We expect a correlation between serum level testosterone and basic cognitive functions such as cognitive speed and cognitive control.
Achtergrond van het onderzoek
Recent research showed a correlation between age related changes in hormone levels and cognitive decline and the emergence of Alzheimer disease in both men and women.
Most research however is conducted in women.
The aim of this study is to further investigate the relation between testosterone level and cognitive functioning in older men. In order to determine testosterone level, total-, SHBG- and albumin bound and bioavailable testosterone will be measured.
Three cognitive computer tests are aimed to measure basal information processing speed, ability to suppress irrelevant stimuli and visuospatial perception, respectively.
Two out-patient groups will be included:
1. BPH-patients in the age of 55-75, and
2. patients with fertility symptoms in the age of 20-45 years.
Doel van het onderzoek
Serum testosterone levels in men will be related to basic cognitive functions, such as mental processing speed and cognitive control.
Onderzoeksopzet
N/A
Onderzoeksproduct en/of interventie
Computer tests.
Publiek
P.O. Box 1738
J.W. Strien, van
Rotterdam 3000 DR
The Netherlands
+31 (0)10 4088787
vanstrien@fsw.eur.nl
Wetenschappelijk
P.O. Box 1738
J.W. Strien, van
Rotterdam 3000 DR
The Netherlands
+31 (0)10 4088787
vanstrien@fsw.eur.nl
Belangrijkste voorwaarden om deel te mogen nemen (Inclusiecriteria)
1. Age between 55 and 75 or age between 20 and 45;
2. Urological complaints suspected to be BPH or fertility symptoms;
3. Subjective healthy impression.
Belangrijkste redenen om niet deel te kunnen nemen (Exclusiecriteria)
N/A
Opzet
Deelname
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Andere (mogelijk minder actuele) registraties in dit register
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In overige registers
| Register | ID |
|---|---|
| NTR-new | NL365 |
| NTR-old | NTR404 |
| Ander register | : A300413 |
| ISRCTN | ISRCTN42645787 |