MIT leads to improved verbal communication in aphasic patients with severe output disorders.
ID
Bron
Verkorte titel
Aandoening
aphasia
verbal apraxia
afasie
verbale apraxie
Ondersteuning
Rotterdam, the Netherlands
Onderzoeksproduct en/of interventie
Uitkomstmaten
Primaire uitkomstmaten
CIU's/minute on the Sabadel:<br>
1. CIU (correct information units): Words in the patients' production that are adequate, comprehensible, relevant, and informative in relation to the target story;<br>
2. In the Sabadel task, the examiner reads a story to the patient. The story is supported by pictures. The patient's task is to retell the story, while looking at the pictures.
Achtergrond van het onderzoek
Background:
Aphasic patients with limited verbal output often show beneficial effect of singing on language production. The MIT was devised to use this capacity in the treatment of aphasia. It uses the melodic aspects of language, such as rythm and intonation. Many case studies have reported spectacular results after MIT. At the moment, there is level III evidence for MIT, mainly for the chronic phase.
Aim:
Establish a higher level of evidence for MIT, both for the chronic phase and for the post-acute phase, when aphasia treatment is regularly provided. Further, it will be investigated whether the efficacy of MIT depends on patient characteristics, such as age, gender, location and seize of the lesion, and severity of the aphasia.
Doel van het onderzoek
MIT leads to improved verbal communication in aphasic patients with severe output disorders.
Onderzoeksopzet
1. T1 (before treatment):
Assessments: Sabadel, repetition of trained and untrained items, AAT, ANELT, PALPA 45 (word comprehension);
2. T2 (after 6 weeks of treatment):
Assessments: Sabadel, repetition of trained and untrained items, AAT, ANELT, PALPA 45 (word comprehension);
3. T3 (after 12 weeks):
Assessments: Sabadel, repetition of trained and untrained items, AAT, ANELT, PALPA 45 (word comprehension).
Onderzoeksproduct en/of interventie
Melodic Intonation Therapy (MIT):
Language production therapy in which the melodic aspects of language (rythm, intonation) are used to train the production of sentences. MIT is given for 6 weeks, 5 hour per week.
Non-MIT (control condition in post-acute group):
Comprehension and production of written sentences. In the control condition, therapy is also given for 6 weeks, 5 hours per week.
No treatment (control condition in chronic group): No individual treatment for 6 weeks. Participation in group treatment (1 time per week) is allowed.
Publiek
Afasieteam
Westersingel 300
A.C. Meulen, van der
Rijndam Rehabilitation Centre
Afasieteam
Westersingel 300
Rotterdam 3015 LJ
The Netherlands
+31 (0)10-2412412, toestel 276
ivandermeulen@rijndam.nl
Wetenschappelijk
Afasieteam
Westersingel 300
A.C. Meulen, van der
Rijndam Rehabilitation Centre
Afasieteam
Westersingel 300
Rotterdam 3015 LJ
The Netherlands
+31 (0)10-2412412, toestel 276
ivandermeulen@rijndam.nl
Belangrijkste voorwaarden om deel te mogen nemen (Inclusiecriteria)
1. Aphasia after LH stroke;
2. Time post onset: 2-3 months (post-acute group) or > 1 year (chronic group);
3. Native speaker of Dutch;
4. Candidate for MIT:
A. Nonfluent (< 50 words per minute);
B. Severe restriction of repetition (AAT subscore repetition <75 and AAT subtest repetition of sentences <11);
C. Articulation problems (AAT spontaneous speech score articulation <3);
D. Good to moderate auditory comprehension (functional comprehension >5 and AAT subtest auditory comprehension > 32).
5. Age: 18-80 years;
6. Right-handed.
Belangrijkste redenen om niet deel te kunnen nemen (Exclusiecriteria)
1. Severe hearing deficit;
2. Premorbid dementia;
3. Recent psychiatric history.
Opzet
Deelname
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In overige registers
Register | ID |
---|---|
NTR-new | NL1850 |
NTR-old | NTR1961 |
Ander register | (I) METC Erasmus MC Rotterdam, (II) Stichting Rotterdams Kinderrevalidatie Fonds Adriaanstichting : (I) MEC-2009-182, (II) 07.08.31-2007/0168 |
ISRCTN | ISRCTN wordt niet meer aangevraagd. |