This study aims to investigate whether A1AT pathology contributes to the development of DD. We will determine the prevalence of A1AT-pathology by genotype analysis in patients with diverticulosis and compare this to a population without…
ID
Bron
Verkorte titel
Aandoening
diverticular disease (DD)
alpha-1-antitrypsin (A1AT) pathology
Ondersteuning
Onderzoeksproduct en/of interventie
Uitkomstmaten
Primaire uitkomstmaten
The main exposure factor is of alpha-1-antitrypsin pathology
Doel van het onderzoek
This study aims to investigate whether A1AT pathology contributes to the development of DD. We will determine the prevalence of A1AT-pathology by genotype analysis in patients with diverticulosis and compare this to a population without diverticulosis. Better understanding of the association between A1AT-pathology and DD could possibly contribute to changes in the treatment of DD.
Onderzoeksopzet
-
Onderzoeksproduct en/of interventie
Venapunction
Publiek
[default]
The Netherlands
Wetenschappelijk
[default]
The Netherlands
Belangrijkste voorwaarden om deel te mogen nemen (Inclusiecriteria)
Research group: the subject has to
- Have acute abdominal pain existing more than two hours’ and less than five days,
- Has a CT-abdomen that shows diverticular disease,
- Age above sixty,
- Be mentally competent, and
- Informed consent.
Control group: the subject has to
- Have acute abdominal pain existing more than two hours’ and less than five days,
- Has a CT-abdomen that shows no diverticular disease,
- Age above sixty,
- Be mentally competent, and
- Informed consent.
Belangrijkste redenen om niet deel te kunnen nemen (Exclusiecriteria)
A potential subject who meets any of the following criteria will be excluded from participation in this study:
- Does not meet the inclusion criteria
- Is mentally incompetent
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In overige registers
| Register | ID |
|---|---|
| NTR-new | NL6112 |
| NTR-old | NTR6251 |
| CCMO | NL55016.094.15 |
| OMON | NL-OMON47360 |