"Early detection of sepsis : a randomized clinical trial."

Evidence suggests that early recognition and time-sensitive resuscitation for patients with severe sepsis and septic shock can significantly improve their outcome. To obtain this objective Protocol Watch was developed as an early warning score system. The purpose of this research was to measure the benefit of the application of this bedside tool in comparison with the standard observation and interpretation of the critical team.

“Can the use of the Protocol Watch improve the earlier detection of sepsis?”
The hypothesis is that the use of the Protocol Watch improves the earlier detection of sepsis with at least 60 minutes.

T 1 --> Differences/delays in time zero of the identification will be compared in both groups. Time zero is set on the moment of detection of possible sepsis (= 2 positive sirs criteria + infection).




T 2 --> Differences/delays in time zero of the first lactate level-test will be compared in both groups.



T 3 --> Differences/delays in time zero of the resuscitation will be compared in both groups. Time zero here is set on the start of the first sepsis bundle, namely the first gift of antibiotics after retrieving blood cultures and the simultaneously start of the fluid resuscitation.

The Protocol watch (PW), designed by Philips Healthcare is a new clinical support application on the patient monitor that assists clinicians in the implementation of the SSC guidelines. Protocol watch monitors the patients for the signs and symptoms of sepsis and notifies you when SIRS/Sepsis conditions occur.