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Effects of crisis cards/plans for people with psychotic illnesses, facilitated through local patient organisation and through clinician, on the number of crisiscontacts with mental health services and the numer of (cumpulsory) admissions.

N/A

Does booster influenza vaccination improve vaccination efficacy in patients with quiescent systemic lupus erythematosus?

SLE patients show a decreased humoral immune response to influenza vaccination, as compared to healthy controls. Furthermore the use of immunosuppressives is of influence on vaccination immunogenicity, it has been demonstrated that the use of drugs…

A Phase II multicenter study to assess the tolerability and efficacy of the addition of Bevacizumab to standard induction therapy in AML and high risk MDS above 60 years.

The hypothesis to be tested is that arm B is tolerable and that the outcome in arm B is better than in arm A.

Effectiveness of adenoidectomy in children with recurrent upper respiratory tract infections.

This is a superiority trial testing the hypothesis that adenoidectomy is more effective than a watchful waiting strategy in children with recurrent upper respiratory tract infections.

Thrombus Aspiration during Percutaneous coronary intervention in Acute myocardial infarction Study (TAPAS).

Thrombus aspiration compared to balloon angioplasty will improve myocardial reperfusion during primary percutaneous coronary intervention.

Gerandomiseerde studie naar de effecten van opereren met LigaSure System op het post-operatief herstel en functioneren van de bekkenbodem na abdominale uterus extirpatie.

Use of vessel sealing reduces postoperative pain and improves postoperative pelvic floor function.

Active plus: implementation and evaluation of two tailored physical activity interventions among the over-fifties.

1. It is hypothesized that participation in the Active plus program contributes to an increase in physical activity behaviour among older adults; 2. Additionally receiving physical and social environmental information results in an extra increase…

The effectiveness of using plantar pressure assessment and monitoring in prescription footwear to reduce re-ulceration rate in diabetic patients: A Randomized Controlled Trial.

Therapeutic footwear of which adequate off-loading properties are guaranteed and monitored by dynamic plantar pressure assessment will result in a reduced plantar re-ulceration rate in diabetic patients with prior plantar foot ulceration compared to…

Efectiveness of adding 'exposure in vivo' techniques to the return-to-work plan of workers with mental health problems: a cluster randomised controlled trial.

Occupational rehabilitation with a gradual return to work based on the principles of exposure in vivo will be more (cost)effective in reducing absenteeism than usual occupational rehabilitation.

Psychophysiological stress mechanisms in chronic inflammatory diseases.

Particularly in patients at risk, the stress-management intervention affect self-reported, immune and neuroendocrine indicators of stress reactivity.

Levetiracetam (Keppra®) in neonates

The use of parenterally administered LEV in neonatal epileptic seizures, detected electrographically, with or without clinical signs, will be safe, and pharmacokinetic and –dynamic properties of the use in neonates will be determined.

Intramedullary Nailing of Diaphyseal Humeral Fractures - T2™ Humeral Nail versus Fixion ® Intramedullary Humeral Nail

Theoretically there are many advantages of using the Fixion ® IM Humeral nail, like a significant reduced surgical and fluoroscopic exposure time. The procedure is simple and minimal invasive. No interlocking screws are needed, thus there is a…

Endometrial aspiration before or after Saline Infusion Sonography (SIS) in case of abnormal uterine bleeding; effect on specimen quality.

The specimen contains less evaluable endometrium after SIS than before SIS.

Small scale living facilities for older people with dementia.

It is hypothesized that residents in small scale living facilities, compared to those in regular nursing home care, have a higher quality of life and functioning. In addition, it is hypothesized that their family caregivers experience less burden…

Laparoscopic ileocolic resection versus infliximab treatment of recurrent distal ileitis in Crohn's disease: a randomized multicenter trial (LIR!C-trial).

Laparoscopic ileocolic resection may be more effective than infliximab treatment in recurrent Crohn´s disease located in the terminal ileum improving quality of life and reducing costs.

Transjugular Intrahepatic Porto-systemic Shunt (TIPS) with Gore-tex(R) covered stent-graft versus endoscopic treatment for secondary prevention of gastro-esophageal variceal bleeding.

TIPS using covered stents will be equally or more effective, cost-effective and safe as/than endoscopic treatment in the secondary prevention of gastro-esophageal variceal bleeding.

Prevention of lymphedema by therapeutic elastic compression hoses; treatment efficacy.

H0: incidence of lymphedema in hose-group equals non-hose group; H1: incidence of lymphedema in hose group does not equal non-hose group.

The Anal Fistula Plug versus the mucosal flap advancement for the treatment of Perianal Fistulas.

The anal fistula plug is superior in the treatment of high transphincteric fistulas compared to the mucosal advancement flap.

Monitoring of exhaled nitric oxide (FENO) to tailor the lowest effective dose of oral corticosteroids in severe asthma (MONOSA-Study).

1. Daily home monitoring of exhaled nitric oxide (FENO) in patients with severe asthma facilitate tapering of oral corticosteroids to the lowest possible dose, leading to a reduction of total corticosteroid consumption; 2. This can be achieved…

Forlax versus Transipeg in constipated children.

Forlax and transipeg are equally effective in treating childhood constipation.