90 resultaten
Parenting is essential for the upbringing of social, mentally and physically healthy children. Parenting interventions can support parents in this process. In general, parent training programs have a positive influence on various outcomes related to…
Our primary objective is to compare the short and medium term (up to 6 months) clinical results in pain and function of the Bauerfeind SecuTec OA brace with only conservative treatment (no brace) in the management of patients with medial knee OA and…
The hypothesis of this study is that a difference in mental well-being can be observed after insertion of an LNG-IUD compared to Cu-IUD insertion.
Hypotheses are that the program will have a positive effect on the health, safety, talent development and socioeconomic health inequities of youth and children in experimental neighborhoods in comparison to control neighborhoods.
Intraoperative video recording combined with synchronous audio recording of the operator's voice during laparoscopic cholecystectomy will more adequately document the essential steps of the surgical procedure compared to the narrative operative…
By using weekly the clinical rule reporter as the medication review system, the number of hospital readmissions in older patients (> 60 years) will be reduced with 5% (from 20% to 15%). For the Netherlands this may translate into prevention…
Our hypothesis is that piperacillin/tazobactam, ciprofloxacin, co-trimoxazole and doxycycline are able to penetrate hepatic cysts.
Group receiving Friso Comfort Next (with milk fat and mixture of different length prebiotics) will have a lower % of all hard stools reported during the 2-mo study period compared to another Young Child Formula (with partially hydrolysed whey…
We hypothesize that storytelling (in the form of a sub-plot), concerning the effects of (un)healthy lifestyle on heart risk, in a popular Dutch TV show for children can cause sustainable positive lifestyle change. Furthermore, we hypothesize that…
LRRK2 activity is linked to central mechanisms of Parkinson’s disease pathology through its role in lysosomal function, and LRRK2 kinase inhibitors, such as DNL201 (IND Number: 133665) represent a new class of therapeutics with potential to address…
The constantly increasing number of aorto-iliac lesions in patients with end-stage renal disease (ESRD) seems to be the result of three main factors: increased recipient age, frequent atherosclerosis accompanying with end-stage renal disease and…
(Experimental) participants who receive information about the availability and use of mindfulness-apps after an MBSR course: (1) report higher frequency of mindfulness practice, (2) report higher mindfulness, lower general psychopathology, and…
PMS increases the chance of problematic use of psychoactive substances. In case of problematic use of psychoactive substances the prevalence of PMS is higher than in case of non problematic use.
Patients with Alzheimer's disease have a significantly reduced function of the visual path compared to healthy people.
We hypothesize that breast cancer organoids will result in a prospective clinical model that is predictive of treatment response.
We hypothesize that it is safe to stop first-line nivolumab or pembrolizumab at confirmed response, while improving quality of life (QoL) and reducing the use of healthcare resources, and costs.
We hypothesize that early mobilisation followed by additional protein intake is more effective in preservation of muscle mass than early mobilisation and optimal nutrition separately.
MRI is a feasible, fast and safe technique for the long term follow up of neonatal and pediatric patient with bronchopulmonary dysplasia.
Performance of the Aeonose™ as a diagnostic tool to detect lung cancer: an external validation study
Primary Objective: To investigate the diagnostic performance of the Aeonose™ to distinguish breath of subjects suspected for lung cancer who are truly diagnosed with lung cancer from subjects suspected for lung cancer in which this diagnosis is…
The proposed study seeks to investigate the effectiveness of a booklet self-help program in the treatment of depressive symptoms among people living with HIV. We will compare the booklet self-help program with an attention only control condition. In…