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We hypothesize that the CPA Talking-with-children-intervention will have a beneficial effect on the mental health and quality of life of maltreated children. We expect that children who participate in the CPA investigation (CPA Talking-with-…
Patients with a BMI > 30 kg/m2 in the ICU have a higher incidence of pressure ulcers and wound infections in the ICU compared with patients with a BMI 18-25kg/m2. They develop them sooner during admittance and the severity and time to…
Electrical stimulation on the foot and lower leg will increase the blood flow and thereby the amount of oxygen to the skin. Our overall hypothesis is that this will help to reduce the risk of decubitus on the heel. The specific hypothesis for this…
Disturbances in the circadian rhythm could be a possible cause for development of delirium.
Simplified FLT PET parameter.
There are two research questions: 1. Does cognitive behavioural therapy (CBT) in groups lead to a significant decrease of fatigue and functional impairment of CFS patients compared to a waiting list condition? 2. For which patient is group therapy a…
Fluorescent near-infrared imaging can accurately detect pancreatic cancer non-invasively during a whipple procedure.
To test the hypothesis that observing the data and waveforms displayed on an respiratory function monitor during the provision of positive pressure ventilation to preterm infants at birth will increase the proportion of tidal volumes within a…
Exploration of the effects of AAT in adults with an Autism Spectrum Disorder (because this study has an explorative character, there is no hypothesis formulated)
Family Group Conferences will improve disability-management self-efficacy and participation in patients with amputation, acquired brain injury and spinal cord injury and their relatives
In each stratum of probability there is a clinically and statistacally significant difference in the functional ability and disease activity score over time (area under the curve) and progression of radiological joint damage after 1 year of follow-…
Stress vulnerability as reflected by cortisolreceptor gene polymorphisms, influences course of bipolar disorder defined by number of episodes, physical health and cognitive functioning.
Education on guidelines, combined with quality targets within the accreditation procedure improves quality of antibiotic prescribing
Muscle hypoxia, either chronic or intermittent (exercise-induced), is responsible for the altered muscle oxidative phenotype in chronic obstructive pulmonary disease and chronic heart failure through modulation of the regulatory molecules PGC-1/…
We hypothesize that group medical appointments will enhance adherence to treatment and self-efficacy in patients with sickle cell disease, as well as increase quality of life, and satisfaction with the treating physician and nurse. When performing…
MPS I patients can be treated with Aldurazyme safely and effectively.
Patient education on extended anticoagulation pros and cons: a journey app in venous thromboembolism
Our hypothesis is that patients whom receive targeted information about VTE and (extended) anticoagulation treatment with the 'patient journey app' on a daily basis in the week preceding their hospital visit will be more satisfied with the…
The Victoria modules are thought to have a positive effect on acknowlegdement for adversities and risk awareness. This can be used to take acceptable risks in rehabilitation process. This will then lead to more societal participation and less…
Previous randomised trials have shown the efficacy of etanercept in RA patients. In this study we will evaluate the respons of etanercept in anti-TNF naive patients compared to patients who have failed other anti-TNF. We will look for clinical…