2127 resultaten
We hypothesize that induction of labour in patients with gestational hypertension, deteriorating chronic hypertension or preeclampsia between 34 and 37 weeks reduce the maternal morbidity but might increase the RDS rate in neonates, compared to…
Systematic, population-based Chlamydia Screening will be able to bring down the prevalence of infections and incidence of longterm complications, provided participation rates are sufficient.
We hypothesize that the CPA Talking-with-children-intervention will have a beneficial effect on the mental health and quality of life of maltreated children. We expect that children who participate in the CPA investigation (CPA Talking-with-…
In the PROHTECT-3 trial, we offer hrHPV testing on self-sampled (cervico-)vaginal specimens obtained by a lavage device. The sensitivity and specificity for high grade CIN and cervical cancer (CIN2+/CIN3+) of two triage strategies of hrHPV positive…
There have been several studies that showed a possible positive effect of electrical stimulation on wound healing. One of the working principles is increasing blood flow. This could mean that by giving frequent electrical stimulation on the foot and…
Screening causes a difference in prostate cancer mortality of 20% or more.
The following hypotheses will be examined: a. patients with multiple sclerosis who become cognitively impaired may experience an increase in pain experience (due to white matter lesions) b. hyperesthesia is known to be predictive of central…
Synflorix (PCV10) and Prevenar-13 (PCV13) are comparable in inducing cellular and humoral immune responses in Dutch infants for the 10 overlapping serotypes in the vaccines. Differences are expected for three serotypes that are present in Prevenar-…
Cap-assisted colonoscopy may improve the adenoma detection rate in CRC screening participants.
A nutrient dense infant formula promotes growth more effectively than current practice.
Evidence based medicine is the standard for current clinical practice. Guidelines and decision rules are developed to support medical decision making. Application of decision rules are supposed to improve efficiency and quality of care by early…
First, it will be investigated which is the best diagnostic tool for imbalance in CP. Second, it will be determined whether balance training can promote balance control in CP, and whether the improvements will be maintained after a follow-up period…
This study aims to implement and evaluate an advance care planning (ACP) intervention for elderly nursing home patients with a limited life expectancy. The intervention consists of ACP discussions integrated with a structured multidisciplinary…
We expect (in the intervention condition as opposed to the control condition): 1. A decrease in children's emotional/behavioral problems and rule-braking behavior; 2. An increase in on-task behavior and teacher's well-being; 3.…
In this explorative study we will examine the impact of daily ischemic preconditioning on brachial artery endothelial function (measured as FMD%, before and after IRI) during 7 days in the non-shunt arm and lower limb in patients with end-stage…
1. 70% of patients will want risk information on the treatment options including prognosis; 2. Medical oncologists face difficulties while trying to judge which patients want the risk information?; 3. Effects of decision aid are positive.
Electrical stimulation on the foot and lower leg will increase the blood flow and thereby the amount of oxygen to the skin. Our overall hypothesis is that this will help to reduce the risk of decubitus on the heel. The specific hypothesis for this…
Disturbances in the circadian rhythm could be a possible cause for development of delirium.
Interhospital transport of IC-patients can be escorted solely by an registered IC-nurse.
PAS III-PC and PR-PAS III-PC are non-inferior compared to plasma PC in terms of recovery, estimated by the 1-hour CCI post transfusion