4587 resultaten
The primary objective is to demonstrate the non-inferiority of bevacizumab to ranibizumab in the treatment of patients with subfoveal CNV secondary to AMD as determined by the change in best-corrected visual acuity in the study eye from baseline to…
To assess the effect of statin therapy on the process of atherosclerosis in type 2 diabetes without manifest cardiovascular disease.
Subjects in the PCD-04 arm will show less anthracyclin-induced cardiotoxicty then subjects in the placebo arm.
We hypothesize that MTX and LEF combination therapy is superior to MTX monotherapy in patients with psoriatic arthritis
The hypothesis is that testosterone supplementation improves functional mobility, quality of life, body composition, cognitive function, aortic stiffness and cardiovascular risk factors, and bone mineral density compared to placebo.
The simplified HALO360 ablation regimen result in an easier and faster ablation procedure, while maintaining efficacy and safety.
The investigational anti-reflux formula will be equivalent to the currently marketed control anti-reflux formula with regard to intestinal tolerance during eight weeks in infants with regurgitation.
A subset of patients with ulcerative colitis have disease limited to only the rectum. Most patients will reach remission with conventional 5-ASA or corticosteroid treatments. However, there have been few studies investigating treatment options in…
The primary objective is to investigate the effectiveness of a personalized 2-year multidomain lifestyle intervention on cognitive performance in older adults at risk of cognitive decline.
Improving the immunological status of HIV-1 infected adults not on antiretroviral therapy through nutritional support.
Dietary management of nutrient deficiencies with the medical food under study has a positive effect on cognitive performance in patients with prodromal Alzheimer's Disease.
ICG alone without being absorbed to albumin can be used for near-infrared fluorescence SLNB in breast cancer patients.
Treatment with an angiotensin II receptor blocker (valsartan) stabilizes or improves the functional performance of the systemic right ventricle.
There will be no significant difference in prevalence of allergy in infants with increased risk for CMA when fed with partially hydrolysed whey protein or extensively hydrolysed casein formula, at the age of 6 months.
DMEK is superior to DSAEK in terms of (rate of) VA rehabilitation.
Depressive symptoms are common in older persons, often associated with poor physical function and vitamin D deficiency (serum 25-hydroxyvitamin D < 50 nmol/l). Simple and cheap interventions to prevent depression are lacking. Vitamin D…
The systemic treatment of rheumatoid arthritis with anti-TNF-a is very successful. In a number of case reports varying success rates of intra-articular injections with the TNF-a blocking agent infliximab have been reported. In this study we want to…
Intranasal insulin will improve development and behaviour in children with Phelan-McDermid syndrome.
We hypothesize that restoration of gut microbiota diversity (by using donor FMT enriched in Desulfovibrio strains) could have explicit beneficial effects on glucose metabolism and NAFLD (via improved fructose catabolism), which is driven by…
The hypothesis is that increasing energy and protein intake in these children will stimulate the rate of protein synthesis, decrease the rate of (muscle)protein breakdown, lead to increased net protein accretion, avoids weight loss and promotes…