1308 resultaten
In the RIO study programme, the efficacy of rimonabant was examined. The next step is to assess the use of rimonabant, its safety and effectiveness in daily practice. In daily practice people also have other diseases, may use other medication and…
There is clear medical need in pediatric high-grade MDS and JMML to control disease pre-SCT without the disadvantages associated with intensive chemotherapy. So far no agents have been successfully applied in this window, or are specifically…
Several open-label pilot studies have shown a promising effect of intrapyloric botulinum toxin injection on symptoms in severe gastroparesis. However, data from randomized, double-blind, placebo-controlled studies are not yet available. We intend to…
1. The point of the skin with best possible transcutaneous nerve stimulation correlates with the point of the skin most superficial to the nerves stimulated within a range of 3 mm; 2. Ultrasound will reveal a significant number of sensitive…
1. ICVAD removal, followed by six months of silicone gel sheet use, will result in a scar width within the normal range, and normal scar structure, and thus will be superior to two months of silicone gel sheets and no gel sheets; 2. A smaller and/…
Mechanical bowel preparation (MBP) is common practice in elective colorectal surgery. In recent literature the value of MBP is subject of discussion. This non-inferiority, randomized study evaluates the value of MBP before colorectal surgery.
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We hypothesize that a treatment algorithm that is based on a simple validated measure of health status (CCQ) improves quality of life (as measured on a separate scale) and other classical COPD outcome measurement parameters such as exacerbation…
The primary research hypotheses are: 1. Patients who follow the Onco-Move program will achieve better physical fitness levels, as assessed by objective performance tests, and will report less fatigue than patients in the usual care control group; 2…
Public health authorities have recognized lack of hand hygiene (HH) as one of the important causes of preventable mortality and morbidity at population level. Both at national (UK, USA, Dutch VMS) and international levels (WHO) poor HH has been…
The on-line intervention will prove to be significantly more effective in improving mood and reducing diabetes-related distress in diabetes patients with minor to moderately severe depression compared to the control condition (CAU, supplementend…
1: Long term use of fluoxetine causes the excitability of the primary motor area of the brain to change 2: Long term administration of fluoxetine causes the muscle activation patterns to change
The hypothesis to be tested that the outcome in arm B is better than in arm A.
Is there a difference in the recurrence rate if you treat a cyst or abscess of the bartholin gland with a marsupialization or placement of a word catheter.
We hypothesize that subjects suffering from hypothalamic dysfunction may have a hyposerotonergic neurotransmission. Therefore we will investigate if there are differences in specific hypothalamic-to-nonspecific [123I]FP-CIT binding ratios using…
Assess of the effect of HD colonoscopy alone or when combined with different I-scan functions compared to standard colonoscopy with respect to adenoma detection rate.
Patients undergoing a minimally invasive oesophagectomy have fewer morbidity, a shorter duration of the intensive care unit (ICU) admission and a better quality of life than following the traditional approach.
1. The treatment group will increase their Theory of Mind skills in comparison to the waitlist control group; 2. The conceptual skills will improve at a higher rate than the practical skills.
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Because of the high cardiovascular risk profile and functional disabilities of obese long-standing type 2 diabetes patients, therapeutic exercise programs have hardly been evaluated in this subpopulation. The current research proposal aims to…