1469 resultaten
Het vergelijken van de standaardbehandeling met intravesicale chemotherapie (Mitomycine C) met intravesicale chemotherapie (met Mitomycine C) in combinatie met locoregionale 70 MHz hyperthermie bij patiënten met een intermediate risico niet-…
The main objectives of this study are: • To gain insight into the effectiveness of the Healthy Working Approach on need for recovery in elderly care workers over one year. • To gain insight into the process of implementing the Healthy Working…
OBJECTIVE: To evaluate the immediate and longer-term effects of early cognitive rehabilitation on cognitive performance and self-reported symptoms/functioning in patients with low-grade gliomas and meningiomas, in a prospective randomized trial.…
The main aim of this study is to test the effectiveness of the intervention ‘Take it personal!’ in decreasing substance use by adolescents (age 14 – 21 years old) with mild to borderline ID en behavioral problems who are admitted to treatment…
In this explorative study we will examine the impact of daily ischemic preconditioning on brachial artery endothelial function (measured as FMD%, before and after IRI) during 7 days in the non-shunt arm and lower limb in patients with end-stage…
(1) Written imaginal exposure results in beneficial effects compared to no-intervention (2) Beneficial effects are greater for written imaginal exposure in the past tense than for written imaginal exposure in the present tense
Our first hypothesis is that both guided and unguided online CBT lead to a decrease in the severity of PCBD, PTSD, and depression symptoms. Our second hypothesis is that people allocated to the guided online CBT group will show a stronger decrease…
This study aims to assess the efficacy and safety of induction and consolidation therapy with Carfilzomib, Pomalidomide and Dexamethasone in subjects with relapsed or refractory multiple myeloma (MM) after prior first-line treatment in the EMN02/…
The aim of this study is to determine a high level of agreement between readings obtained from the plasma levels and the Roche Accu-Chek Inform II.
Daily showering followed by immediate application of emollient is better for the clinical outcome of mild to moderate AD in children, when compared to once weekly showering followed by immediate application of emollient.
Primary aim: 1. To investigate whether differences exist in the mitochondrial energy generating capacity of skeletal muscle of statin users with SAMS compared to statin users without SAMS and controls (non-statin users). Secondary aims: 2A. To…
In line with a previous pilot study we hypothesize that 3MDR will significantly decrease PTSD symptom severity in treatment resistant veterans with chronic PTSD in comparison with treatment as usual.
The RAINBOW study: Rheumatoid Arthritis ImplemeNtation of Biological dose Optimization in real World
We hypothesize that a multifaceted implementation strategy can stimulate the use of tight control and bDMARD dose optimization in clinical practice, measured by decreased bDMARD use and non-inferiority on disease activity at 18 months.
We hypothesize that therapeutic drug monitoring of risperidone in children with an autism spectrum disorder and comorbid behavioral problems will reduce metabolic side effect burden, while retaining clinical effectiveness.
1) The knowledge of the legal aspects of health care and medical negligence/errors among medical residents is larger in the intervention group than for the control group 2) The flipped classroom model is effective as a teaching method in post…
The hypothesis of the TRANSFORM II study is the non-inferiority of Sirolimus Coated Balloon versus Everolimus Eluting Stent in terms of Target Lesion Failure
We hypothesize that iABM patients, relative to controls, will show less addiction problems, increased health, reduced physical and psychological complaints, and reduced use of health care post-intervention and at 6 & 12 month FU Further, we…
This is a superiority trial testing the hypothesis that analgesic ear drops as added to usual care (oral analgesics with/without antibiotics) provide superior ear pain relief over usual care in children aged 1 to 6 years with a GP-diagnosis of AOM…
The aim of this study is to characterize the proportion and extent of patients who return-to-work and who enter (partial) disability pension in a “labouring class” of patient infected by COVID-19, who were admitted to the hospital for medium- and/or…
We hypothesize, that SCD patients ending with mixed mononuclear chimerism after non-myeloablative HSCT with alemtuzumab/TBI conditioning will preserve their immune response to vaccinations administered prior to the transplantation and will therefore…