163 resultaten
First, it will be investigated which is the best diagnostic tool for imbalance in CP. Second, it will be determined whether balance training can promote balance control in CP, and whether the improvements will be maintained after a follow-up period…
Does MS grey matter pathology progress faster in regions with more damage in connected white matter?
Our hypothesis is that MS grey matter pathology, and thereby disease burden and clinical outcome, can be better predicted by looking at damage in the connected white matter in early RRMS patients
This study will be an open observational study with the objective to test the feasibility of the mDLS. The variability of the methodology over time will be assessed. Blood flow and coagulation status assessed by mDLS and LSCI will be compared with…
Rationale: There is no cure for dementia. Physical activity could be an alternative to medications in an effort to slow cognitive decline In healthy elderly subjects physical activity leads to improved cognition. Objective: Part 1: Main objective:…
We hypothesize that the quality of diabetes treatment, measured as glycaemic control, is worse in patients with T2DM and colorectal- and breast cancer treated with curative intent, compared to T2DM patients without cancer, at 1 and 2 years after…
Extension of SAD PK/PD Model, confirmation of SAD PD effects
Family Integrated Care in Single Family Rooms improves neurodevelopmental outcome in preterm infants
Surgical treatment (DAIR on day 10) will result in a 50% reduction rate of revision for PJI up to one year after primary TKA/THA compared to nonsurgical treatment. Consequently surgical treatment is more (cost) effective compared to nonsurgical…
We hypothesize that implantation asymmetry (IS), angular rotation (AR) and undersizing (AUI) are predictors for the occurring of subsidence. Furthermore we believe subsidence is related to decreased clinical outcomes. Presumably Total Disc…
Patients using vitamin K-antagonists are under intensive supervision of anticoagulation clinics in the Netherlands. Despite the supervision, not all patients achieve a time in therapeutic range above 65%. A proposed reason is a reduced adherence to…
Multiple Sclerosis is a complex disease with a multifactorial cause. Progression in MS arises and persists by complex inflammatory reactions leading to neurodegeneration and tissue disturbance. Progressive MS is characterised by a degenerative…
Detection, diagnosis, staging, treatment outcome and prognosis of patients with a malignancy of the upper aerodigestive tract improve when Narrow Band Imaging in combination with standard (White Light) endoscopy is used.
Clients with multiple problems supported by a CARm trained labour expert will improve on functioning and work status. The primary aim of the study is to evaluate the effectiveness of an integrated, client centred and strengths based approach…
To assess the tolerability and efficacy of the addition of oral selinexor to standard induction therapy.
1. This study will investigate if the group therapy is effective based on the functional outcome variables (pain, mobility, activity and disability) in patients with non-specific chronic low back pain. 2. This study will compare the effectiveness of…
We expect higher participant scores for self-efficacy, behavioral intentions and evaluation for the photo story intervention compared to a comparable traditional brochure. We expect that the majoritiy of participants prefers the photo story…