778 resultaten
The following hypotheses will be examined: a. patients with multiple sclerosis who become cognitively impaired may experience an increase in pain experience (due to white matter lesions) b. hyperesthesia is known to be predictive of central…
This study aims to implement and evaluate an advance care planning (ACP) intervention for elderly nursing home patients with a limited life expectancy. The intervention consists of ACP discussions integrated with a structured multidisciplinary…
We hypothesize that there is no difference in clinical and radiological outcome when using PSG for UKA compared with results from the literature describing results from conventional UKA surgical techniques.
The primary hypothesis is that the effect of tubal flushing with oil-based contrast results in higher ongoing pregnancy rates compared to water-based contrast medium.
The aim of this study is to develop and evaluate a health behavior change and social network enhancement intervention for low-income households in Apeldoorn who receive care for multiple problems (such as financial debts, domestic violence,…
screening for cardiovascular diseases will reduce coronary heart disease-related mortality and morbidity
Hypothesis 1: Participants in both conditions (experimental and placebo) will show a reduction in gamble problem severity immediately post-intervention and at 3-and 6-month follow-ups. However, participants in the experimental condition will show a…
To develop a dosing nomogram of irinotecan in patients homozygous polymorphic for UGT1A1*28 and/or UGT1A1*93 in order to reduce the incidence of severe irinotecan-associated toxicity, defined as febrile neutropenia in the first 2 cycles (amendment…
A combination therapy (MDT and TESIs) is effective and cost-effective compared to usual care among herniated nucleus pulpos patients with an indication for a lumbar herniated disc surgery
- How effective are the Acts of Kindness exercises with and without reflection compared to an active control condition and wait-list condition on mental well-being, flourishing, positive relations, gratitude, positive and negative emotions, optimism…
In EPF, the sequential combination of mifepristone with misoprostol is superior to the use of misoprostol alone in terms of complete evacuation of products of conception, patient satisfaction, complications, side effects and costs.
- brain activation and connectivity during emotion regulation, thinking about future events, inferring on emotions of others and rest are different in patients with a recent suicide attempt compared to patient controls and healthy controls - brain…
The expectation of this study is that shorter duration of plaster cast immobilization is beneficial for the patients.
The primary objective of the present study is to investigate the effectiveness of the Resource Groups (RG) on patient outcomes compared to care as usual alone for people with severe mental illnesses. It is hypothesized that participation in the RG…
Patients with Type 2 diabetes have been shown to have an increased risk for developing cancer, especially obesity related cancers. There is some evidence that within the class of sulfonylureas there is a difference in cancer risk; gliclazide could…
A Community One Health approach (bringing human and animal health together at the community level) improves disease surveillance efforts by Community Health Workers, health knowledge and behavior and physical health in study populations.
Feasibility and reliability of prehospital triage in patients with thoracic complaints/pain appropriate to a suspicious ACS
This study will evaluate the effectiveness of IPAS, with and without additional support, to improve objectively measured PA levels. We expect that IPAS will raise the level of PA more than normal care (UC) with a higher expected effect for IPAS +…
The WALK gait retraining program is more effective to treat patients with symptomatic mild to moderate knee OA and an extension deficit, compared to a standardised treatment protocol based on the KNGF (royal Dutch association of physiotherapists)…