20 resultaten
The present study aims at the improvement of the treatment of children with PTSD by examining the effectiveness of a brief intensive exposure therapy (IET) for children with PTSD using a multiple baseline design (patients are randomly assigned to…
We hypothesise that there would be no significant difference between the preoperative planning between different orthopedic surgeons.
Fentanyl is a strong opioïd and is highly lipophilic. Fentanyl pharmacokinetics are characterised by large inter- and intrapatient differences, which may have serious consequences for the activity and toxicity profile of this drug. The use of…
Recent pre-clinical experiments demonstrated that sorafenib in Oatp1b2(-/-) mice had 8-fold increased sorafenib-glucuronide blood concentrations.OATP1B1 and 1B3 are highly expressed in the human liver and facilitate the hepatocellular uptake of…
1. Active sniffing decreases appetite; 2. Food choice is mainly influenced by the food odour that was perceived first.
The addition of a specific fibre mixture to a breakfast cereal will impact the blood glucose response.
pressure, heat and the combination of both do not negatively influence platelet function.
Reduction in dietary sodium intake decreases blood pressure, extracellular volume and renal damage in renal transplant recipients.
Spinal anesthesia induces several alterations in normal brain processes. Firstly, loss of afferent information increases pain sensitivity. In our previous study on the effects of spinal anesthesia (P11.221) we showed that subjects felt more pain…
Obesity is a growing world wide problem. In The Netherlands, about 10% of all men and women have a BMI of 30 kg/m2 or more. Obesity is a chronic, uncurable metabolic disorder, which is characterised by excessive fatstorage at unfavorable places.…
Inhalation of a single regular dose steroid (200ugr Qvar autohaler) with a stretched upper airway (achieved by leaning forward and flexing the head backwards) will protect more against exercise induced asthma compared to inhalation of a single…
Which of 2 feeding strategies for children during chemotherapy induced mucositis is optimal for the patient: an elementary diet, containing only simple macronutrients administered via continuous enteral drip; or total parenteral nutrition.
Primary Objective: • Is CBM-I successful in changing the cognitive bias in patients with cluster-C personality disorders or personality disorder NOS? Secondary Objective(s): • Will patients following CBM-I show a significant reduction in symptoms…
We hypothesize (1) that an anticipatory reward will lead to more activation in reward related areas such as the striatum, amygdala, and dopaminergic midbrain compared to a consummatory reward (preceded by an anticipatory reward). Furthermore, we…
Primary hypothesis: Based on the aforementioned study results we hypothesize that a single exercise bout performed under hypoxic conditions will reduce the 24-hour post-exercise quantity of hyperglycemic episodes more efficiently in comparison with…
Obesity is a growing world wide problem. In The Netherlands, about 10% of all men and women have a BMI of 30 kg/m2 or more. Obesity is a chronic, uncurable metabolic disorder, which is characterised by excessive fatstorage at unfavorable places.…
Roux-en-Y Bariatric (RYGB) surgery is a successful approach to morbid obesity. In this procedure, the stomach is reduced to a small 'gastric pouch' . The duodenum is bypassed by connecting the jejunum this gastric pouch. The duodenum is…
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There are many orthoses available to treat the symptoms caused by thumb carpometacarpal osteoarthritis. It is however not known which type reduces pain the most, which orthosis is preferred by patients and which factors influence compliance with…
The aim of this phase I study is to assess the extent of intestinal absorption of rivaroxaban and dabigatran etexilate in adult patients with short bowel syndrome requiring long-term TPN.