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The flavonoid-drug interaction could potentially lead to higher nintedanib absorption by the gastro-intestinal tract. This would cause higher systemic bioavailability and lower local gastro-intestinal drug concentrations. Furthermore, inter-patient…
In this randomised controlled study, the effects of art therapy is examined on psychological functioning of patients with a personality disorder. It is expected that art therapy results in less personality pathology, more acceptance, and less…
The post-prandial rise in total amino acid, proline and glycine concentration following a single bout of resistance exercise will be the highest in the 20 gr whey combined with 10 gr collagen compared to all other test drinks
Standing leads to better performance on cognitive tasks regarding executive functioning.
Overall, diagnostic accuracy will be lower on subjected-to-bias than on not-subjected-to-bias cases, but the difference in accuracy will be smaller in the group of physicians with higher knowledge of critical diagnostic features. Overall, the…
Primary 1. An immediate invasive approach (immediate angiography and revascularization when appropriate) results in a reduction of the combined incidence of death, re-infarction or recurrent ischemia at 30 days follow-up. Secondary 1. An immediate…
SPT is as effective as MRA in sleep-position dependent OSA
Participation in a health check-up results in a statistically significant positive change in health-related behaviour after 6 months.
To investigate whether either chlorhexidine-alcohol or iodine-alcohol based skin antiseptics is more protective against surgical site infections.
Using inhaled volatile anaesthetic agents as the primary sedative during mechanically ventilation in patients with COVID-19-associated ARDS improves gas exchange and ventilatory support requirements
We hypothesize that the ceftriaxone monotherapy strategy is non-inferior for mortality and for nephrotoxicity a strategy of ceftriaxone monotherapy is superior to a strategy of cefuroxime combined with short course aminoglycosides.
Flexible RPD's have a higher impact on OHRQoL compared to acrylic RPD's.
We hypothesize that usage of a crisis checklists in simulated patients will results in: 1. Better collaboration within exposed teams. 2. A reduction in the number of omitted safety critical steps. 3. Faster completion of safety critical…
Based on current literature we expect that Mindfulness-Based Stress Reduction decrease burnout symptoms and improves wellbeing and the quality of care in medical residents.
The aim of this study is to show whether switching patients from a once daily (QD) to a twice daily (BID) dosing schedule will lead to a significant increase in pharmacokinetic exposure, measured as Cmin and AUC0-24h.
Cognitive remediation focused on executive functioning for patients with bipolar disorder improves executive functioning on (1) personal goals in daily life, and (2) general well-being. Exploratory hypotheses: - Cognitive remediation focused on…
Intravitreal injections are used more and more frequently in ophthalmology. This trend is mostly caused by the arrival of anti-VEGF agents used for age-related macular degeneration, diabetic macular edema and macular edema secondary to retinal vein…