485 resultaten
The peripheral chemoreceptors in the carotid bodies are sensitive to changes in the tensions of oxygen and carbon dioxide in the arterial blood and protect the body against hypoxia, hyper- and hypocapnia and acidosis/alkalosis. The ventilatory…
Objectives: 1. To investigate the added effects of eplerenone on top of ACEi, with and without dietary sodium restriction, on residual albuminuria, hypertension, and tubular injury markers, in patients with diabetic nephropathy; 2. To investigate…
human milk will phase separate and thereby empty differently from infant formula
The main objective of this study is to investigate to what extent the acute effects of MDMA on cognitive function, prolactin and cortisol levels, body temperature, heart rate and blood pressure are influenced by co-exposure to THC.
Inhalation of once daily double dose of inhaled tobramycin targeted to the small airways by the Akita (1x 300 mg instead of 2x 150 mg) is more effective in reducing small airways obstruction compared with standard of treatment: twice daily…
It is hypothesized that the outcome of the primary outcome parameter will be different for the test product compared to the control product.
The goal of the study is to: 1. Improve daily functioning in patients with schizophrenia; 2. To improve behavioral observation in psychiatric nurses; 3. To implement CAT in the usual treatment of patients with severe mental illness.
Preterm infants often require supplemental oxygen to prevent hypoxemia and hyperoxemia. Conditions that have been associated with organ damage and an increased mortality. Newly developed techniques incorporated in the ventilator provide the…
Adding specific components designed to target three risk factors for child maltreatment (parental stress, parental anger, and post-traumatic stress symptoms) to an evidence-based home visiting program alleviates these specific risk factors.
-
- Intradialytic protein ingestion increases plasma total amino acid concentrations throughout hemodialysis compared to placebo. - Intradialytic exercise increases amino acid loss into the dialysate in fasted patients and decreases amino acid loss…
Increasing age is associated with a decrease in step length, gait speed, and mobility. Gait speed predicts numerous clinical conditions, including independence and mortality. A variety of exercise interventions are highly effective in maintaining…
The main of the study is to gain more information about the sedative effects of two doses (20 and 40 mg) of bilastine and to assess the effect of repeated dosing on the road driving ability. It is expected that no differences will be detected…
We hypothesise that in the Subacromial Pain Syndrome (SAPS), a differentiation between primary peripheral (i.e. (peri)articular) and secondary pain due to altered processing of pain, i.e. central pain sensitisation, is needed. We further hypothesise…
Roux-en-Y Bariatric (RYGB) surgery is a successful approach to morbid obesity. In this procedure, the stomach is reduced to a small 'gastric pouch' . The duodenum is bypassed by connecting the jejunum this gastric pouch. The duodenum is…
Oral sodium butyrate use in subjects with type 1 diabetes will lead to an altered innate immune system response, ultimately improving beta cell function and glucose regulation.
1. At baseline, memory performance and neuroendocrine reactions are expected to differ between novice MDMA (< 10 ecstasy exposures) users and heavy/experienced MDMA users (>100 ecstasy exposures). It is hypothesized that heavy MDMA…
It is expected that PROMISE leads to more enthusaistic natal care professionals for helping preganant women quit smoking and for discussing strategies for smoking cessation more often and that this results in a more effective delivery of stop-…
We hypothesize that implementation of a workers's health surveillance and consecutive interventions will lead to prevention of injury and disability, health improvement, and eventually sustained employment.