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We hypothesize that the ceftriaxone monotherapy strategy is non-inferior for mortality and for nephrotoxicity a strategy of ceftriaxone monotherapy is superior to a strategy of cefuroxime combined with short course aminoglycosides.
The primary objective is to determine whether JWH-018 can be safely administered in healthy volunteers in doses up to 3 mg. Therefore participants will be continuously monitored by a medical doctor and vital signs, laboratory clinical safety and…
Wheelchair mobility skills training and wheelchair fitness training will both increase the level of physical activity in wheelchair using children and adolescents. Wheelchair fitness training prior to wheelchair mobility skills training will show a…
Based on previous studies, we will expect that ambroxol improves neurological manifestations in patients with GD3.
The administration of propranolol will inhibit the increase in dermal blood flow (DBF) induced by capsaicin application.
Lifestyle coaching will lead to reduced fatigue and improved quality of life
We hypothesize that the UC Diet (UCD) can improve induction of remission rates when administered with a 5ASA regimen to pediatric patients with mild-moderate UC vs. 5ASA regimen alone.
The objective of this study is offloading the peak plantar pressure in Diabetic patients with loss of protective sensation by using the self-adjusting insoles and individually optimized rocker profiles. The secondary objective is to evaluate the…
Protein metabolism consists of amino acid incorporation and amino acid oxidation. We have developed a breath test which is able to measure the oxidation of ingested 13C-protein. We hypothesize that a diet low in protein before the breath test will…
4 week n-3 PUFA supplementation will enhance daily muscle protein synthesis rates in older men on a standardized diet.
Are hemodynamic values obtained by the non invasive hemodynamic measuring device TL-400 comparable with the values obtained by the standard invasive hemodynamic measuring devices (transpulmonary thermodilution (TPTD) (PiCCO system; Pulsion Medical…
Co-ingesting keto-analogues of branched-chain AAs along with protein during HD attenuates HD-initiated muscle catabolism.
Significantly more patients will express an overall preference for ICI-P versus ICI-B
Capillary malformations (¡®port-wine stains¡¯) are congenital abnormalities of the capillary vessels of the skin, causing a red or purple color. Laser therapy is currently the only widely accepted treatment option, but treatment response is…
We expect that participants (young people between 12 and 18 years in a generally healthy population) when asked to exaggerate / feign will show a significantly higher score on Self-report Symptom Inventory's(SRSI) pseudo-symptoms scale than…
We hypothesize that a single night of short sleep duration (4 hours), compared to normal sleep duration (8 hours) reduces metabolic flexibility, increases insulin resistance and thereby reduces HPA-reactivity. Furthermore, we hypothesize that a…
It is expected that PROMISE leads to more enthusaistic natal care professionals for helping preganant women quit smoking and for discussing strategies for smoking cessation more often and that this results in a more effective delivery of stop-…
We postulate that a set target range of 92%-96% will result in a more stable SpO2 and accompanying reduction of time spent with an SpO2 <91% and similar or less time >96% when compared to a target range of 91%-95%.
I. Test whether psychological and psychophysiological indices of PC are differentially affected by fantasizing vs. mindfulness in remitted MDD patients and HC: Pre-and peri-intervention changes will be examined using within-subject and between-group…