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Infant formulae with higher levels of milk fat result in improved fatty acids absorption as compared to standard formula.
Acid-reducing drugs, such as PPIs, may profoundly decrease solubility and, as a result, (negatively) affect the bioavailability of afatinib. Since a PPI is often used concomitantly during afatinib therapy, this DDI confronts physicians, patients,…
I. Test whether psychological and psychophysiological indices of PC are differentially affected by fantasizing vs. mindfulness in remitted MDD patients and HC: Pre-and peri-intervention changes will be examined using within-subject and between-group…
Preoperative planning with x-ray-based PSI have comparable outcome as 3D used MRI-based PSI resulting in indirectly reduced costs on storage of implants and instruments.
Co-ingesting keto-analogues of branched-chain AAs along with protein during HD attenuates HD-initiated muscle catabolism.
It is hypothesized that the outcome of the primary outcome parameter will be different for the test product compared to the control product.
Preterm infants often require supplemental oxygen to prevent hypoxemia and hyperoxemia. Conditions that have been associated with organ damage and an increased mortality. Newly developed techniques incorporated in the ventilator provide the…
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We hypothesise that in the Subacromial Pain Syndrome (SAPS), a differentiation between primary peripheral (i.e. (peri)articular) and secondary pain due to altered processing of pain, i.e. central pain sensitisation, is needed. We further hypothesise…
We hypothesize that dietary nitrate supplementation improves muscle strength and muscle endurance performance.
We expect the number of seizures to decrease with the introduction of a seizure dog. Besides the effect of seizure dogs on seizure frequency, we expect an impact on participation, well-being, health-related quality of life, healthcare resource use (…
The objective of this study is offloading the peak plantar pressure in Diabetic patients with loss of protective sensation by using the self-adjusting insoles and individually optimized rocker profiles. The secondary objective is to evaluate the…
The hypothesis formulation for the primary outcome parameter is: -H0: The effect of using test product (Product A) is equal to the effect of using control product (Product B) with respect to the area under the curve (AUC(0-360))of serum P. -H1: The…
We expect that participants (young people between 12 and 18 years in a generally healthy population) when asked to exaggerate / feign will show a significantly higher score on Self-report Symptom Inventory's(SRSI) pseudo-symptoms scale than…
We expect that younger children have a higher learning capacity at the end-effector level, thus they should be faster in learning to handle the visuomotor transformation task than older children.
Doxepin hydrochloride 5% cream significantly reduces pruritus in burn patients in comparison with a placebo cream
Patients with ALS are routinely prescribed riluzole, the only registered drug for the treatment of ALS. This study will evaluate the concentration-effect relationship of riluzole (100 mg) and retigabine (300 mg) on axonal excitability measures. In…
If COMET increases the saliency of positive autobiographical memories, then memories that are activated during COMET (relative to no intervention control) should show an increase over time on all primary outcome measures, irrespective of medication…
We postulate that a set target range of 92%-96% will result in a more stable SpO2 and accompanying reduction of time spent with an SpO2 <91% and similar or less time >96% when compared to a target range of 91%-95%.