241 resultaten
The main objective is to determine the change in CS parameters upon administration of tapentadol in comparison to pregabalin in patients suffering from chronic pain that has a visceral or deep somatic origin.
1. DKD patients are salt-sensitive due to a decreased sodium buffering capacity (damaged ESL). As a consequence a high sodium diet will lead to water retention, resulting in increased ECF, body weight and blood pressure. 2. CKD patients are salt-…
We want to examine the effects of both the adjustable rocker profile and the self-adjusting insole on in-shoe pressure in this patient group. We expect to find similar reductions in pressure as previously found in healthy subjects. Also, the…
We want to determine the influence and safety of probenecid on sorafenib pharmacokinetics. By inhibiting the OAT6 transporter there might be a faborable effect on Hand-foot syndrome
The main objective is to evaluate the efficacy and safety of phenytoin cream in patients with neuropathic pain due to CIAP
Our hypothesis is that contratile segment impedance is a marker for EoE-disease activity (histological remission or active disease)
Main hypothesis The BENEFIT intervention will significantly increase the number of CVD patients that can maintain the healthy lifestyle behavior most relevant to them for at least one year, compared to care-as-usual. Secondary hypothesis The BENEFIT…
We hypothesize that the metabolic effects of acute infusion of acetate are different in insulin resistant subjects compared to lean subjects.
Which design of cognitive aid (emergency manual) is easier to use and results in less missed critical actions during anesthetic emergencies
A new health system is being validated on heart rate variability; galvanic skin response and oxygen saturation.
Better glucose control during the closed loop system compared to standard open loop therapy
A nursing nutrition intervention improves protein and energy intake and performance based on hand grip strength compared to usual care.
Use of any mask (surgical or N95) in a standard day of work for hospital staff, may result in subjective feelings of dyspnoea. These symptoms of dyspnoea do not correlate to a decreased oxygen saturation, but do correlate to baseline participant…
The hypothesis is that the Manometric brace is superior to conventional plaster braces in terms of patient satisfaction, compliance and patient preference. For pain and hand function, no superior outcomes are expected for the Manometric brace…
We hypothesize that methylphenidate improves ADHD manifestations in children and adults with SMS.
We hypothesize that the MMP could be cost-efficient for a part of the patients, but that for some patients a more simple prosthesis would be more cost-efficient. Therefore, we do not expect big differences in cost-effectiveness between the MMP and…
The treatment with ciNPT results in a superior healing when compared to the standard treatment (no ciNPT). The rationale behind the secondary outcome is that this treatment leads to improvement of scar quality in comparison to the standard treatment…
We hypothesize that E171 induces gene expression changes in the colon that explain the inflammatory mechanism of E171 in the colon, which facilitate the development of colorectal cancer. In addition, inflammatory markers will be increased in the…
We hypothesize that TRH effectively antagonize opioid-induced respiratory depression