232 resultaten
We hypothesize that PHA-022121 will be more effective in both the treatment and prophylaxis of acute angioedema attacks in patients with acquired C1-inhibitor deficiency when compared to placebo.
The main objective is to determine the change in CS parameters upon administration of tapentadol in comparison to pregabalin in patients suffering from chronic pain that has a visceral or deep somatic origin.
I. Test whether psychological and psychophysiological indices of PC are differentially affected by fantasizing vs. mindfulness in remitted MDD patients and HC: Pre-and peri-intervention changes will be examined using within-subject and between-group…
We want to examine the effects of both the adjustable rocker profile and the self-adjusting insole on in-shoe pressure in this patient group. We expect to find similar reductions in pressure as previously found in healthy subjects. Also, the…
We want to determine the influence and safety of probenecid on sorafenib pharmacokinetics. By inhibiting the OAT6 transporter there might be a faborable effect on Hand-foot syndrome
It is expected that oliceridine has a better profile concerning dose-related analgesia and dose-related side effects, compared to morphine.
Is voor het verkrijgen van echogeleide IV toegang een korte as benadering of een lange as benadering superieur wanneer deze wordt uitgevoerd door SEH-verpleegkundigen zonder ervaring met echografie.
A new health system is being validated on heart rate variability; galvanic skin response and oxygen saturation.
The hypothesis is that the Manometric brace is superior to conventional plaster braces in terms of patient satisfaction, compliance and patient preference. For pain and hand function, no superior outcomes are expected for the Manometric brace…
Lifestyle coaching will lead to reduced fatigue and improved quality of life
The treatment with ciNPT results in a superior healing when compared to the standard treatment (no ciNPT). The rationale behind the secondary outcome is that this treatment leads to improvement of scar quality in comparison to the standard treatment…
We hypothesize that TRH effectively antagonize opioid-induced respiratory depression
Electroconvulsive therapy (ECT) is the most effective treatment for severe depressions. Unfortunately, several cognitive side effects with a large pallet of different manifestations and impact often occur. For instance, postictal agitation ((PIA)…
We hypothesize that the UC Diet (UCD) can improve induction of remission rates when administered with a 5ASA regimen to pediatric patients with mild-moderate UC vs. 5ASA regimen alone.
Based on previous studies, we will expect that ambroxol improves neurological manifestations in patients with GD3.
Atherosclerosis is characterized by a persistent inflammation of the arterial wall. Monocyte-derived macrophages are the most abundant immune cells in atherosclerotic plaques. It has recently been shown that not only immune cells of the adaptive…
We hypothesize that methylphenidate improves ADHD manifestations in adults with (late-diagnosed) PKU.
The study hypothesis is that FFCiH will maintain or improve functional status and physical activity in hospitalized stroke and geriatric patients compared to usual care.